Abstract: The present application describes disubstituted pyrazolines and triazolines of formulae I and II:
or pharmaceutically acceptable salt forms thereof, wherein one of M1 and M2 maybe N and D may be a variety of N-containing groups, which are useful as inhibitors of factor Xa.
Abstract: The present application describes oxygen and sulfur containing heteroaromatics and derivatives thereof of formula
or pharmaceutically acceptable salt or prodrug forms thereof, wherein J is O or S and D may be C(═NH)NH2, which are useful as inhibitors of factor Xa.
Type:
Grant
Filed:
December 22, 1997
Date of Patent:
February 13, 2001
Assignee:
Dupont Pharmaceuticals Company
Inventors:
James Russell Pruitt, John Matthew Fevig, Mimi Lifen Quan, Donald Joseph Phillip Pinto