Patents Represented by Attorney Dean A. Ersfeld
  • Patent number: 7579359
    Abstract: Imidazo-containing compounds (e.g., imidazonaphthyridines, imidazopyridines, imidazoquinolines, and imidazote-trahydroquinolines) with an alkoxy substituent at the 1-position, pharmaceutical compositions containing the compounds and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
    Type: Grant
    Filed: September 1, 2005
    Date of Patent: August 25, 2009
    Assignee: 3M Innovative Properties Company
    Inventors: Larry R. Krepski, Daniel E. Duffy, John F. Gerster, Joan T. Moseman
  • Patent number: 7576144
    Abstract: Carbosilane monomers that include the following structural features: at least two Si-arylene bonds; at least one (meth)acrylate moiety; no Si—O bonds; and preferably at least two silicon atoms.
    Type: Grant
    Filed: July 13, 2005
    Date of Patent: August 18, 2009
    Assignee: 3M Innovative Properties Company
    Inventors: Kevin M. Lewandowski, Ahmed S. Abuelyaman, Babu N. Gaddam, Sumita B. Mitra, Brian N. Holmes, Adrian S. Eckert, Peter Bissinger
  • Patent number: 7481975
    Abstract: The present invention provides a hydrogen peroxide indicator that includes a substrate on which is disposed an indicator composition that includes at least one of a select group of colorants. As a result of contact with hydrogen peroxide, the colorants change color, and even become colorless, thereby providing an indication of the presence of hydrogen peroxide.
    Type: Grant
    Filed: July 14, 2004
    Date of Patent: January 27, 2009
    Assignee: 3M Innovative Properties Company
    Inventor: David M. Read
  • Patent number: 7468272
    Abstract: A biological soil detector and a method for detecting bio soil are provided. The biological soil detector has a solid support member; a specific indicator immobilized on the solid support member, the specific indicator having a material sensitive to the presence of blood; and the solid support and specific indicator positioned within or on a retaining member to readily contact a liquid that has been used to contact a surface. In the method for detecting bio soil, the method includes the following steps: contacting the surface with a liquid; after the liquid has contacted the surface, contacting the liquid with the solid support member and the specific indicator of the detector described herein; and inspecting the solid support member for a detectable response to determine whether the specific indicator has interacted with biological soil.
    Type: Grant
    Filed: October 18, 2004
    Date of Patent: December 23, 2008
    Assignee: 3M Innovative Properties Company
    Inventors: Sailaja Chandrapati, Bernard A. Gonzalez, Bonnie J. Hovde, Kevin D. Landgrebe
  • Patent number: 7465536
    Abstract: A biological soil detector is provided, having: a solid support member; a specific indicator immobilized on the solid support member; and a retaining member which holds the solid support, the retaining member and solid support are configured so that the solid support will readily contact a surface being tested for the presence of biological soil. A method for the use of the detector is also provided, the method including the following steps: contacting the biological soil detector with a surface; withdrawing the biological soil detector from the surface; and inspecting the solid support member of the detector to determine whether the specific indicator immobilized has interacted with biological soil. In still another aspect, the invention provides biological soil detector and a method for using the detector in which the detector includes: a solid support member that has been treated with at least one amine or quaternary functional coating; and a specific indicator immobilized on the coating.
    Type: Grant
    Filed: May 10, 2004
    Date of Patent: December 16, 2008
    Assignee: 3M Innovative Properties Company
    Inventors: Bernard A. Gonzalez, Kevin D. Landgrebe, Kimberley D. Klepzig, Sailaja Chandrapati, Susannah C. Clear, Mark W. Nelson, Elizabeth E. Endler
  • Patent number: 7452924
    Abstract: The present invention is directed to dental compositions that can be used as adhesives for bonding a dental material to a dental structure surface and/or as a dental restorative material. The dental composition is preferably applied to a dental structure surface under conditions effective to etch the dental structure surface.
    Type: Grant
    Filed: August 11, 2004
    Date of Patent: November 18, 2008
    Assignees: 3M Espe AG, 3M Innovative Properties Company
    Inventors: Steven M. Aasen, Ahmed S. Abuelyaman, Hendrik M. Grupp, Miriam Hansen, Thomas Klettke, Guenther Lechner, Kevin M. Lewandowski, Thomas Luchterhandt, Sumita B. Mitra, Prabhakara S. Rao, Victoria A. Russell, Michael S. Wendland
  • Patent number: 7449499
    Abstract: The present invention is directed to dental compositions that can be used as adhesives for bonding a dental material to a dental structure surface and/or as a dental restorative material. The dental composition is preferably applied to a dental structure surface under conditions effective to etch the dental structure surface.
    Type: Grant
    Filed: August 11, 2004
    Date of Patent: November 11, 2008
    Assignee: 3M Innovative Properties Company
    Inventors: Bradley D. Craig, Steven M Aasen, Ahmed S. Abuelyaman, Reinhold Hecht, Thomas Luchterhandt, Prabhakara S. Rao, Brian A. Shukla, Markus Watermann
  • Patent number: 7442760
    Abstract: Electroactive polymeric arylenes and intermediates useful for making such polymers are disclosed. The present invention also provides electroactive compositions comprising the electroactive polymeric arylenes, organic electronic devices which comprise these polymers and compositions, and methods of fabricating these devices.
    Type: Grant
    Filed: March 17, 2006
    Date of Patent: October 28, 2008
    Assignee: 3M Innovative Properties Company
    Inventors: Ralph R. Roberts, James G. Bentsen, Yingbo Li
  • Patent number: 7288550
    Abstract: Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain thioether functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.
    Type: Grant
    Filed: May 19, 2005
    Date of Patent: October 30, 2007
    Assignee: 3M Innovative Properties Company
    Inventors: Joseph F. Dellaria, Matthew R. Radmer, Bryon A. Merrill
  • Patent number: 7220758
    Abstract: Imidazopyridine compounds that contain an ether or thioether functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are also disclosed.
    Type: Grant
    Filed: July 24, 2006
    Date of Patent: May 22, 2007
    Assignee: 3M Innovative Properties Company
    Inventors: Joseph F. Dellaria, Kyle J. Lindstrom, Luke T. Dressel, Philip D. Heppner, John R. Jacobsen, Joan T. Moseman, William H. Moser, Matthew R. Radmer, Doris Stoermer
  • Patent number: 7214675
    Abstract: Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain ether and urea functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.
    Type: Grant
    Filed: May 19, 2005
    Date of Patent: May 8, 2007
    Assignee: 3M Innovative Properties Company
    Inventor: George W. Griesgraber
  • Patent number: 7199131
    Abstract: Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain sulfonamide or sulfonamide functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.
    Type: Grant
    Filed: April 7, 2005
    Date of Patent: April 3, 2007
    Assignee: 3M Innovative Properties Company
    Inventor: Kyle J. Lindstrom
  • Patent number: 7163947
    Abstract: 1-Amino 1H-imidazoquinoline compounds, pharmaceutical compositions containing the compounds, intermediates, and methods of making and methods of use of these compounds as immunomodulators, for modulating cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
    Type: Grant
    Filed: September 3, 2004
    Date of Patent: January 16, 2007
    Assignee: 3M Innovative Properties Company
    Inventors: George W. Griesgraber, Karl J. Manske
  • Patent number: 7157453
    Abstract: Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain urea, thiourea, acylurea, or sulfonylurea functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.
    Type: Grant
    Filed: January 20, 2005
    Date of Patent: January 2, 2007
    Assignee: 3M Innovation Properties Company
    Inventors: Stephen L. Crooks, Michael J. Rice
  • Patent number: 7148232
    Abstract: Thiazolo-, oxazolo- and selenazolo[4,5-c]quinolin-4-amines and analogs thereof are described including methods of manufacture and the use of novel intermediates. The compounds are immunomodulators and induce cytokine biosynthesis, including interferon and/or tumor biosynthesis, necrosis factor, and inhibit the T-helper-type 2 immune response. The compounds are further useful in the treatment of viral and neoplastic diseases.
    Type: Grant
    Filed: August 25, 2004
    Date of Patent: December 12, 2006
    Assignee: 3M Innovative Properties Company
    Inventors: John F. Gerster, Kyle J. Lindstrom, Gregory J. Marszalek
  • Patent number: 7132429
    Abstract: Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain ether and sulfonamide or sulfamide functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.
    Type: Grant
    Filed: February 28, 2005
    Date of Patent: November 7, 2006
    Assignee: 3M Innovative Properties Company
    Inventors: George W. Griesgraber, Bryon A. Merrill, Ralph R. Roberts, Ai-Ping Wei
  • Patent number: 7125890
    Abstract: Imidazopyridine compounds that contain an ether or thioether functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are also disclosed.
    Type: Grant
    Filed: August 11, 2004
    Date of Patent: October 24, 2006
    Assignee: 3M Innovative Properties Company
    Inventors: Joseph F. Dellaria, Kyle J. Lindstrom, Luke T. Dressel, Daniel E. Duffy, Philip D. Heppner, John R. Jacobsen, Joan T. Moseman, William H. Moser, Matthew R. Radmer, Doris Stoermer, Bernhard M. Zimmermann
  • Patent number: 7115622
    Abstract: Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain ether and amide functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.
    Type: Grant
    Filed: February 28, 2005
    Date of Patent: October 3, 2006
    Assignee: 3M Innovative Properties Company
    Inventors: Stephen L. Crooks, George W. Griesgraber, Philip D. Heppner, Bryon A. Merrill
  • Patent number: 7112677
    Abstract: 1H-imidazo dimer compounds are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.
    Type: Grant
    Filed: October 8, 2004
    Date of Patent: September 26, 2006
    Assignee: 3M Innovative Properties Company
    Inventor: George W. Griesgraber
  • Patent number: 7098221
    Abstract: Imidazopyridine compounds that contain amide functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.
    Type: Grant
    Filed: August 10, 2005
    Date of Patent: August 29, 2006
    Assignee: 3M Innovative Properties Company
    Inventors: Philip D. Heppner, Kyle J. Lindstrom, Bryon A. Merrill