Abstract: A method and apparatus for performing an assay process, featuring providing microbeads in a solution, each microbead having a particle substrate with a grating with a superposition of different predetermined regular periodic variations of the index of refraction disposed in the particle along a grating axis and indicative of a code; placing the microbeads on an alignment substrate; reading codes of the microbeads and the position thereof on the alignment substrate; reading the fluorescence on each microbead and the position order thereof on the alignment substrate; and determining an assay result based on bead position order and bead code of the earlier reading steps.
Type:
Grant
Filed:
November 30, 2006
Date of Patent:
February 9, 2010
Assignee:
Electronics and Telecommunications Resarch Institute
Inventors:
John A. Moon, Alan D. Kersey, Martin A. Putnam, Tuo Li