Patents Represented by Attorney, Agent or Law Firm Debbie K. Wright
  • Patent number: 6669977
    Abstract: The present invention is directed to a setting system for use in the making of gelatin desserts comprising gelatin and an anionic hydrocolloid gum wherein the weight ratio of gelatin to anionic hydrocolloid gum is approximately 250-375:1. Through the use of such a setting system, lower gelatin use of up to 10% or more can be realized while achieving an increase in gel strength of up to about 20%.
    Type: Grant
    Filed: March 1, 2001
    Date of Patent: December 30, 2003
    Assignee: Kraft Foods Holdings, Inc.
    Inventors: Jimbay Peter Loh, Dreena Ann Dulin, Alice Shen Cha
  • Patent number: 5759852
    Abstract: Disclosed are expression vectors useful as vectors in recombinant methods to facilitate expression of exogenous genes in E. coli. Specifically, the disclosed expression vector has the following elements in operable linkage: the PL6m promoter, the TAT32 ribosome binding site and a gene encoding a heterologous polypeptide, Also disclosed are E. coli host cells transformed with this expression vector.
    Type: Grant
    Filed: June 27, 1994
    Date of Patent: June 2, 1998
    Assignee: Pharmacia & UpJohn Company
    Inventors: Richard J. Kirschner, John Edward Mott, Frances M. Eckenrode, David Paul Brunner
  • Patent number: 5510256
    Abstract: The present invention is based upon the discovery that proteins made from genes that include the CD4 sequence in its cDNA can make additional polypeptides as a result of internal translation initiation. This invention is thus directed to DNA sequences which eliminate internal initiation expression in sCD4.
    Type: Grant
    Filed: December 29, 1994
    Date of Patent: April 23, 1996
    Assignee: The Upjohn Company
    Inventors: Richard J. Kirschner, John E. Mott, Frances M. Eckenrode, David P. Brunner
  • Patent number: 5340724
    Abstract: The present invention relates to the use of taxol dependent cells, e.g. Tax 2-4 CHO cell line, as the basis of a screen for taxol or taxol-like compounds.
    Type: Grant
    Filed: April 25, 1991
    Date of Patent: August 23, 1994
    Assignee: The Upjohn Company
    Inventor: Irene Abraham
  • Patent number: 5213795
    Abstract: The present invention provides an inactivated encephalomyocarditis virus (EMCV) vaccine produced from swine isolates which protects swine from diseases caused by EMCV. The vaccine is produced from swine isolates and protects against respiratory problems, myocardial and pulmonary inflammation and necrosis, and confers protection against reproductive disorders resulting from some strains of the virus.
    Type: Grant
    Filed: October 24, 1990
    Date of Patent: May 25, 1993
    Assignee: Oxford
    Inventors: Jack H. Carlson, Han S. Joo
  • Patent number: 5196542
    Abstract: Provided are cyclic hydrocarbons of Formula I ##STR1## with an aminoalkyl sidechain that are useful for treating phospholipase A2 mediated conditions, diabetes, and obesity.
    Type: Grant
    Filed: February 20, 1991
    Date of Patent: March 23, 1993
    Assignee: The Upjohn Company
    Inventors: Roy A. Johnson, Gordon L. Bundy, Gilbert A. Youngdale, Douglas R. Morton, Donald P. Wallach, deceased
  • Patent number: 5187299
    Abstract: Provided are cyclic hydrocarbons of Formula I ##STR1## with an aminoalkyl sidechain.
    Type: Grant
    Filed: November 13, 1991
    Date of Patent: February 16, 1993
    Assignee: The Upjohn Company
    Inventors: Roy A. Johnson, Gordon L. Bundy, Gilbert A. Youngdale, Douglas R. Morton, Donald P. Wallach, deceased, Wallach, Legal Representative, by Vera M.
  • Patent number: 5145874
    Abstract: Provided are cyclic hydrocarbons of Formula I ##STR1## with an aminoalkyl sidechain that are useful for treating phospholipase A2 mediated conditions, diabetes, and obesity.
    Type: Grant
    Filed: February 25, 1991
    Date of Patent: September 8, 1992
    Assignee: The Upjohn Company
    Inventors: Roy A. Johnson, Gordon L. Bundy, Gilbert A. Youngdale, Douglas R. Morton, Donald P. Wallach, deceased, by Vera M. Wallach, legal representative
  • Patent number: 5134164
    Abstract: The present invention provides a method for treating or preventing certain metabolic disorders comprising the systemic administration of 3-guanidinopropionic acid.
    Type: Grant
    Filed: August 14, 1991
    Date of Patent: July 28, 1992
    Assignee: The Upjohn Company
    Inventor: Martin D. Meglasson
  • Patent number: 5132324
    Abstract: The present invention provides a method for treating or preventing certain metabolic disorders comprising the systemic administration of 3-guanidinopropionic acid.
    Type: Grant
    Filed: June 10, 1991
    Date of Patent: July 21, 1992
    Assignee: The Upjohn Company
    Inventor: Martin D. Meglasson
  • Patent number: 5106741
    Abstract: This invention discloses human tissue plasminogen activator (TPA) analogs. The analogs are TPA-like molecules that have had the native domain regions either rearranged, delected, added or a combination thereof. The analogs are the product of the expression of recombinant DNA also described herein. Additonally, the present invention described replication and expression plasmids containing the TPA-coding DNA sequences described above and suitable host microorganisms that are capable of expressing the TPA analogs after becoming transformed with an appropriate plasmid.
    Type: Grant
    Filed: June 12, 1991
    Date of Patent: April 21, 1992
    Assignee: The Upjohn Company
    Inventors: Keith R. Marotti, Edward F. Rehberg, Nicole Y. Theriault
  • Patent number: 5075434
    Abstract: This invention is a compound of formula 1 and pharmaceutically acceptable salts thereof; ##STR1## wherein R.sub.1 is fluorine, chlorine or bromine; wherein R.sub.2 is hydrogen or (C.sub.1 -C.sub.3) alkyl; wherein n is one or 2; wherein R.sub.3 is phenyl, 2-furyl, 3-furyl, 2-thienyl, 3-thienyl, 2-pyridinyl, 3-pyridinyl, 4-pyridinyl; wherein phenyl is optionally substituted with one substituent selected from the group consisting of halogen, trifluoromethyl or sulfonamide. These compounds are useful as hypoglycemic agents.
    Type: Grant
    Filed: September 20, 1990
    Date of Patent: December 24, 1991
    Assignee: The Upjohn Company
    Inventor: Gilbert A. Youngdale
  • Patent number: 5001234
    Abstract: This invention provides novel cyclic hydrocarbons of the formula: ##STR1## wherein R is selected from the group consisting of CH.sub.2 .dbd.CH--CH.sub.2 --, HO--CH.sub.2 CH.sub.2 CH.sub.2 --, and CH.sub.3 ;wherein R.sub.1 is selected from the group consisting of m-trifluoromethylphenylmethyl, 2-thienylmethyl, and p-aminosulfonylphenylethyl;wherein R.sub.2 and R.sub.3 are methyl or hydrogen;wherein R.sub.4 is hydrogen or --OH;a compound of the formula ##STR2## wherein R is (CH.sub.3).sub.2 NCH.sub.2 CH.sub.2 CH.sub.2 -- or NH.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 --;or a compound of the formula ##STR3## wherein the dashed line indicates that the 2-3 bond is saturated or unsaturated and, wherein R is hydrogen or methyl.These compounds are useful for inhibiting adverse physiological symptoms associated with phospholipase A.sub.2 and for treating hyperglycemia associated diseases such as diabetes and obesity.
    Type: Grant
    Filed: October 16, 1989
    Date of Patent: March 19, 1991
    Assignee: The Upjohn Company
    Inventors: Gordon L. Bundy, Gilbert A. Youngdale