Abstract: Methods and compositions for treating CF by mobilizing mutant forms of CFTR, which retain at least some functional activity, to the plasma membrane where they can mediate chloride ion transport are disclosed.
Abstract: In accordance with the present invention, there is provided a needle guard assembly for a hypodermic syringe or other fluid transfer device that offers optimal protection for preventing accidental puncture by a needle after it has been used, maintaining the sterility of a needle prior to use, indicating prior use, preventing reuse, and facilitating safe disposal of a needle after use/injection.