Patents Represented by Attorney Deborah A. Savislak

Find this attorney in the Justia Lawyer Directory

  • IL-21 antagonists
    Patent number: 7186805
    Abstract: The polypeptides, and the polynucleotides encoding for them, described herein are IL-21 antagonists that bind with specificity and exhibit an EC50 that is not detectable in receptor binding studies. These molecules have mutations in the D helix of the IL-21 molecule, and can be used to inhibit the activity of IL-21 with its cognate receptor.
    Type: Grant
    Filed: July 1, 2005
    Date of Patent: March 6, 2007
    Assignee: ZymoGenetics, Inc.
    Inventors: Scott R. Presnell, James W. West, Julia E. Novak