Abstract: Disclosed are devices having improved anti-microbial resistance to bacteria and fungus. Indwelling devices, such as catheters and the like, include low amounts of gentian violet, or a combination of gentian violet and silver nitrate. Methods for preparing the treated devices using alcohol and similar solvents are also detailed. The devices may be made of polyurethane, silicone, or other similarly absorptive material. Methods of inhibiting infection and long-term catheter management with the described devices are also disclosed.
Type:
Grant
Filed:
November 1, 1995
Date of Patent:
January 20, 1998
Assignee:
Texas Tech University Health Sciences Center