Abstract: The present invention is directed to the purification and commercialization of therapeutic polypeptides that have. In one aspect of the invention, a method of purifying Interferon ?-1b using size exclusion chromatography is provided. In another aspect of the invention, a method of purifying a polypeptide using size chromatography is provided. A third aspect provides a method of commercializing a polypeptide.
Type:
Grant
Filed:
September 9, 2004
Date of Patent:
March 4, 2008
Assignee:
Chiron Corporation
Inventors:
Patricio T. Riquelme, Corazon Terciano Victa, Walter Joseph Crosier, John Tharin Wendell