Abstract: The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis, cancer, tumor growth, atherosclerosis, age related macular degeneration, diabetic retinopathy, inflammatory diseases, and the like in mammals.
Type:
Grant
Filed:
February 1, 2002
Date of Patent:
July 1, 2003
Assignee:
Merck & Co., Inc.
Inventors:
Mark T. Bilodeau, George D. Hartman, Peter J. Manley