Abstract: This invention provides cholesterol absorption inhibitors of Formula I: and the pharmaceutically acceptable salts and esters thereof. The compounds are useful for lowering plasma cholesterol levels, particularly LDL cholesterol, and for treating and preventing atherosclerosis and atherosclerotic disease events.
Type:
Grant
Filed:
October 4, 2006
Date of Patent:
April 27, 2010
Assignee:
Merck & Co., Inc.
Inventors:
Robert J. DeVita, Gregori J. Morriello, Peter Lin