Patents Represented by Attorney, Agent or Law Firm Dike, Bronstein, et al., IP Group
  • DNA coding for a human vasoconstrictive peptide and use thereof
    Patent number: 6365725
    Abstract: Disclosed are (1) a DNA containing a cDNA segment coding for human endothelin-2 (SEQ ID NO:1), (2) a precursor of human endothelin-2 (SEQ ID NO:2), (3) a transformant carrying a DNA containing a cDNA segment coding for human endothelin-2, and (4) a method for preparing mature human endothelin-2 which comprises culturing the transformant described in (3), accumulating a protein in a culture medium, and collecting the same, whereby human endothelin-2 and the precursors thereof can be produced in large amounts.
    Type: Grant
    Filed: July 10, 1991
    Date of Patent: April 2, 2002
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Haruo Onda, Shoichi Ohkubo