Abstract: A printing plate assembly for use in flexographic printing application is provided which includes an integral carrier layer, one or more cushion layers, and one or more photopolymer layers. The photopolymer layer(s) in the integral assembly are provided with relief images using digital imaging photopolymerization, which eliminates the need for a back exposure step and provides a precise relief depth for the plate.
Abstract: A delivery device and a method for administering a fluid from a fluid reservoir, wherein an unintended free flow of the fluid from the reservoir to a recipient is reliably prevented, are disclosed. The delivery device has a tank for the fluid; a fluid delivery device which delivers the fluid from the tank; a valve body providing an input hole and an output hole; and an infusion set in order to guide the fluid from the tank to a distal end of the delivery device. The delivery device further provides a shutter assembly which is or can be mounted to the valve body and prevents the fluid from flowing inside the infusion set when the fluid exhibits a pressure which is lower than a predefined pressure.
Type:
Grant
Filed:
February 11, 2010
Date of Patent:
August 28, 2012
Assignee:
Roche Diagnostics International AG
Inventors:
Pascal Johner, Jean-Noel Fehr, Michel Saint-Ghislain, Hanspeter Niklaus, Felix Fuchs
Abstract: A method of object classification based upon fusion of a remote sensing system and a natural imaging system is provided. The method includes detecting an object using the remote sensing system. An angle of view of a video camera of the natural imaging system is varied. An image including the object is generated using the natural imaging system. The natural imaging system may zoom in on the object. The image represented in either pixel or transformed space is compared to a plurality of templates via a competition based neural network learning algorithm. Each template has an associated label determined statistically. The template with a closest match to the image is determined. The image may be assigned the label associated with the relative location of the object, the relative speed of the object, and the label of the template determined statistically to be the closest match to the image.
Type:
Grant
Filed:
February 25, 2009
Date of Patent:
August 28, 2012
Assignee:
Toyota Motor Engineering & Manufacturing North America, Inc.
Abstract: The invention discloses the cloning, expression and uses of a chimeric fusion protein with superior chaperone and folding activities compared to the wild type chaperones. This invention relates to a chimeric fusion protein encoded by a recombinant DNA molecule containing nucleotide sequences coding for a polypeptide binding segment of a non-human chaperone protein and nucleotide sequences coding for an FK506 binding protein (FKBP) or an FK506-binding-protein-like domain (FKBP-like domain).
Type:
Grant
Filed:
April 11, 2011
Date of Patent:
August 21, 2012
Assignee:
Roche Diagnostics Operations, Inc.
Inventors:
Christian Scholz, Elke Faatz, Peter Schaarschmidt, Urban Schmitt
Abstract: Special polarization states are generated that have unique focusing properties that may be used to create extremely strong longitudinal fields. Combined with surface plasmon excitation, these polarization states can be used in apertureless near-field scanning optical microscopy systems. A radially polarized beam is directed into a plasmon-generating optical fiber comprising a metal coated, tapered, apertureless tip. The apertureless tip excites surface plasmon waves and direct the surface plasmon waves to the tip when a radially polarized beam propagates along the plasmon-generating optical fiber. An objective lens collects the near field optical signals from a sample positioned adjacent to the apertureless. Potential spatial resolution of the apertureless NSOM could reach beyond 10 nm. Such strong field enhancement allows the development of a reliable nano-Raman system that can measure mechanical as well as chemical compositions of samples with resolution beyond 10 nm.
Abstract: Display buttons and vehicle consoles include etched lenses operable to diffract light provided by a light source within a vehicle console such that the light emitted from the display button diverges from the first pathway within the button housing into a secondary pathway outside of the display button.
Type:
Grant
Filed:
September 17, 2009
Date of Patent:
August 21, 2012
Assignee:
Toyota Motor Engineering & Manufacturing North America, Inc.
Abstract: Embodiments included herein include a projectile system. At least one embodiment of the a projectile system includes hollow portion and a weight that is movably secured within the hollow portion of the projectile insert system. Some embodiments include an attracting device rigidly secured at a first end of the hollow portion, the attracting device removably securing the weight, where the hollow portion provides a pathway for the weight to travel when a force is exerted on the projectile insert system that causes the weight to become unsecured from the attracting device.
Abstract: The invention relates to a medical device for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a therapeutic agent and an additive. In certain embodiments, the additive has a hydrophilic part and a drug affinity part, wherein the drug affinity part is at least one of a hydrophobic part, a part that has an affinity to the therapeutic agent by hydrogen bonding, and a part that has an affinity to the therapeutic agent by van der Waals interactions. In embodiments, the additive is water-soluble. In further embodiments, the additive is at least one of a surfactant and a chemical compound, and the chemical compound has a molecular weight of from 80 to 750 or has more than four hydroxyl groups.
Abstract: Embodiments of a patient transport cot comprise a height adjustment component coupled to the patient transport cot and configured to raise or lower the cot to a plurality of heights. The patient transport cot further comprises an electronic height indicator coupled to the patient transport cot and comprising at least one height sensor, wherein each height sensor represents a target cot height. The electronic height indicator further comprises at least one visual display component coupled to the sensor, wherein the height sensor is triggered when the cot is adjusted to the target cot height setting represented by the height sensor. The triggering of the height sensor actuates the visual display component.
Abstract: Methods for predicting the performance risk of a paint component are disclosed. The methods include providing a proposed paint formulation, wherein the proposed paint formulation comprises at least one paint component, and identifying previous paint formulations comprising the paint component. The methods further include evaluating formulation similarities between the previous paint formulations and the proposed paint formulation, assigning formulation similarity scores based on the formulation similarities, and determining a paint component risk score for the paint component based on the formulation similarity scores. The proposed paint formulation may be utilized in a manufacturing application when the paint component risk score satisfies a manufacturing threshold value.
Type:
Grant
Filed:
December 9, 2009
Date of Patent:
August 14, 2012
Assignee:
Toyota Motor Engineering & Manufacturing North America, Inc.
Abstract: The present invention automates the process of receiving transportation documentation and producing advance loading manifests therefrom to optimize load planning and dynamic product shipment and delivery control. Methods provide for receipt of the transportation documentation, initial preparation, and transmission of the documentation from on board a vehicle or while the vehicle is in transit.
Abstract: Methods of treating depression, binge eating disorder, narcolepsy, excessive daytime sleepiness, substance use disorders, and Prader Willi syndrome, disorders characterized at least in part by hypocortisolemia and decreased activity of the hypothalamic-pituitary-adrenal (HPA) axis, and disorders related to disturbances in circadian rhythm, comprising the step of administering an effective amount of a histamine type 3 (H3) receptor antagonist, such as betahistine or its pharmaceutically acceptable salts, or its metabolites to an individual.
Abstract: A device for sampling, transporting and/or disposal of fluid media in the nl and ?l-range comprises a substrate with and open or closed capillary-like groove or channel respectively, the substrate with the open or closed groove or capillary respectively is bent or arcuated at least at one location. The substrate comprises at least one end into which the open closed capillary-like groove or channel respectively is extended, which end is shaped according to its application or use as e.g. needle-like, straight-lined cut, tip-like, at least most half circle-shape, rounded, etc.
Type:
Grant
Filed:
November 22, 2005
Date of Patent:
August 14, 2012
Assignee:
Roche Diagnostics Operations, Inc.
Inventors:
Stephan Korner, Patrick Griss, Emad Sarofim, Carlo Effenhauser
Abstract: The invention relates to a medical device for delivering a therapeutic agent to a tissue. The medical device has a layer overlying the exterior surface of the medical device. The layer contains a therapeutic agent and an additive. In certain embodiments, the additive has a hydrophilic part and a drug affinity part, wherein the drug affinity part is at least one of a hydrophobic part, a part that has an affinity to the therapeutic agent by hydrogen bonding, and a part that has an affinity to the therapeutic agent by van der Waals interactions. In embodiments, the additive is water-soluble. In further embodiments, the additive is at least one of a surfactant and a chemical compound, and the chemical compound has a molecular weight of from 80 to 750 or has more than four hydroxyl groups.
Abstract: A brake system for a rollator may include a brake handle, a braking device operatively coupled to the brake handle, and a gear rim mechanically coupled to at least one wheel of the rollator. The brake handle may be pivotally attached to a frame of the rollator and comprises a service-brake position and a parking-brake position while the braking device may be disposed on the frame of the rollator proximate the at least one wheel. When the brake handle is in a service-brake position, a braking member of the braking device is frictionally engaged with an inner portion of a rim of the at least one wheel thereby braking the wheel. When the handle is in a parking-brake position, the braking member of the braking device is engaged with teeth of the gear rim thereby preventing the wheel from rotating.
Abstract: A catalyst composition for facilitating the oxidation of soot from diesel engine exhaust is provided. The catalyst composition includes a catalytic metal selected from Pt, Pd, Pt—Pd, Ag, or combinations thereof, an active metal oxide component containing Cu and La, and a support selected from alumina, silica, zirconia, or combinations thereof. The platinum group metal loading of the composition is less than about 20 g/ft3. The catalyst composition may be provided on a diesel particulate filter by impregnating the filter with an alumina, silica or zirconia sol solution modified with glycerol and/or saccharose, impregnating the filter with a stabilizing solution, and impregnating the filter with a solution containing the active metal oxide precursor(s) and the catalytic metal precursor(s). The resulting catalyst coated diesel particulate filter provides effective soot oxidation, exhibits good thermal stability, has a high BET surface area, and exhibits minimal backpressure.
Type:
Grant
Filed:
September 23, 2011
Date of Patent:
August 14, 2012
Assignee:
Ford Global Technologies, LLC
Inventors:
Albert Chigapov, Alexei Dubkov, Brendan Carberry
Abstract: An incubator transporter interface assembly for releasably securing an incubator to a transporter is provided. The interface assembly includes equipment mounts that pivot together between an engaging position and a disengaging position so as to engage and disengage, respectively, the incubator to and from a secured state with the interface assembly.
Abstract: A flow shifting fuel cell with water separator. The water separator is used to control the amount of moisture that passes through the anode flowpath of one or more fuel cells in one or more fuel cell stacks. The water separator is made up of a housing to direct the flow of a moisture-bearing fluid as well as act as a collection and container for separated moisture. Fluid that is cyclically passing through the fuel cell stack as part of its flow shifting mode of operation oscillates back and forth across a separation chamber formed within the water separator, thereby allowing bidirectional control of the moisture content within the fluid. A drain is formed in the separation chamber to allow removal of condensed water.
Type:
Grant
Filed:
July 19, 2007
Date of Patent:
August 7, 2012
Assignee:
GM Global Technology Operations LLC
Inventors:
Andreas Koenekamp, Dirk Rensink, Marcus Koch, Michael Hahn