Patents Represented by Law Firm Doms, Smith, Lande & Rose
  • Patent number: 4224198
    Abstract: Small, round, bio-compatible microspheres capable of covalently bonding proteins and having a uniform diameter below about 3500 A are prepared by substantially instantaneously initiating polymerization of an aqueous emulsion containing no more than 35% total monomer including an acrylic monomer substituted with a covalently bondable group such as hydroxyl, amino or carboxyl and a minor amount of a cross-linking agent.
    Type: Grant
    Filed: May 26, 1978
    Date of Patent: September 23, 1980
    Assignee: California Institute of Technology
    Inventors: Alan Rembaum, Shiao-Ping S. Yen, William J. Dreyer