Abstract: A scanning and data acquisition method and apparatus for three dimensional (3D) computerized tomography (CT) imaging of an ROI in an object, wherein data is calculated on a plurality of line segments L formed in cone beam projection data acquired on a detector at a plurality of source positions. The endpoints of the line segments L formed in the data acquired at each of the source positions is determined by a data combination mask having its bounds formed by cone beam projection onto the plane of the detector of portions of the source scan path that are above and below the source position that acquired the cone beam data in which the data for the line segments L are being calculated.