Abstract: Multifunctional proteins having M-CSF activity and at least one other bioactivity not found together in a single naturally occuring molecule are described. These multifunctional M-CSF proteins can be produced by the expression of fused genes which are also described. These multifunctional M-CSF proteins have increased therapeutic potential.
Type:
Grant
Filed:
December 12, 1994
Date of Patent:
October 22, 1996
Assignee:
Cetus Onocology Corporation
Inventors:
Peter Ralph, George Martin, Michael Piatak, James W. Larrick