Abstract: A selenium-containing aqueous stream may be used as a quenching water stream and optionally a cutting water stream in a delayed coking process to effectuate the removal of selenium from the selenium-containing aqueous stream resulting in the formation of a selenium-coke product. In addition, selenium may be concentrated in selenium-containing stripped sour water streams by recycling the stream in one or more hydroprocessing units and one or more sour water stripper units and subsequently removed by using a portion of the selenium-containing stripped sour water stream as a quenching water stream and optionally a cutting water stream in a delayed coking process.
Type:
Grant
Filed:
September 15, 1994
Date of Patent:
December 8, 1998
Assignee:
Shell Oil Company
Inventors:
Raymond Tom Fong, John Bernard Rodden, Jack Thomas Veal, Charles Lee Meyer, Michael Norris Treybig, Coley Jerald Williams, Richard Joseph Horvath
Abstract: Populations of black flies can be controlled by introducing an effective amount of water soluble detergent range ethoxylated alcohols into the aquatic habitats where black fly larvae are found.
Abstract: This invention describes a novel human brain Na.sup.+ -dependent inorganic phosphate cotransporter, designated the hBNPI protein. This invention also encompasses nucleic acids encoding this protein, or a fragment thereof, as well as methods employing this protein and the nucleic acid compounds.
Abstract: This invention describes a novel human brain Na.sup.+ -dependent inorganic phosphate cotransporter, designated the hBNPI protein. This invention also encompasses nucleic acids encoding this protein, or a fragment thereof, as well as methods employing this protein and the nucleic acid compounds.
Abstract: Trityl derivatives useful as "linkers" for preparation of imunoconjugates comprising drugs end antibodies are provided. Immunoconjugates and processes for their preparation and use are also provided. This invention also provides for prodrugs comprising a substituted trityl group conjugated with a drug of choice as well as methods of using the imunoconjugates and prodrugs of this invention.
Abstract: Phthalyl amidase is an enzyme previously unknown in the art that catalyzes removal of the phthalyl moiety from phthalyl-containing amides. The current invention provides said phthalyl amidase, means for producing it by culturing the natural organism from which the activity was identified, and methods for using said phthalyl amidase to remove the phthalyl moiety from phthalyl-containing amides.
Type:
Grant
Filed:
May 22, 1995
Date of Patent:
March 4, 1997
Assignee:
Eli Lilly and Company
Inventors:
Barbara S. Briggs, Milton J. Zmijewski, Jr.
Abstract: Immunoconjugates of antibodies or antigen-recognizing fragments of antibodies and monovalent cytotoxic drug derivatives make use of .beta.-alanine derived linkers wherein the antibody or fragment thereof is attached to the linker's carboxy group via an ester or amide group and the drug is attached through the linker's 2-position methylene group. Intermediates, compositions and methods of use also are provided.
Type:
Grant
Filed:
March 30, 1993
Date of Patent:
September 17, 1996
Assignee:
Eli Lilly and Company
Inventors:
Russell L. Barton, Deborah L. Guttman-Carlisle, Gary A. Koppel
Abstract: Phthalyl amidase is an enzyme previously unknown in the art that catalyzes removal of the phthalyl moiety from phthalyl-containing amides. The current invention provides DNA compounds encoding the phthalyl amidase enzyme and methods for expressing such compounds. The present invention also provides recombinant DNA vectors encoding phthalyl amidase and host cells transformed with these DNA vectors.
Abstract: Phthalyl amidase is an enzyme previously unknown in the art that catalyzes removal of the phthalyl moiety from phthalyl-containing amides. The current invention provides a phthalyl amidase, a method for producing it by culturing the natural organism from which the activity was identified, and methods for using the phthalyl amidase to remove the phthalyl moiety from phthalyl-containing amides. The enzyme is isolated from Xanthobacter agilis.
Type:
Grant
Filed:
May 22, 1995
Date of Patent:
July 2, 1996
Assignee:
Eli Lilly and Company
Inventors:
Barbara S. Briggs, Milton J. Zmijewski, Jr.
Abstract: Phthalyl amidase is an enzyme previously unknown in the art that catalyzes removal of the phthalyl moiety from phthalyl-containing amides. The current invention provides 2 phthalyl amidase, 2 method for producing it by culturing the natural organism from which the activity was identified, and methods for using the phthalyl amidase to remove the phthalyl moiety from phthalyl-containing amides. The ezyme is isolated from Xanthobacter agilis.
Type:
Grant
Filed:
May 22, 1995
Date of Patent:
July 2, 1996
Assignee:
Eli Lilly and Company
Inventors:
Barbara S. Briggs, Milton J. Zmijewski, Jr.