Abstract: A CD cleaning and labeling device comprises an upper case engageable with a lower case to form a compartment therein. The upper case has an actuating means to drive a driving means and at least one cleaning means. The lower case has a base for carrying a CD or a CD label, a driven means engageable with the driving means and a movable sticking seat which may be lifted above the base at an extension position for receiving the CD or be pressed downward by means of the closed upper case for performing the CD cleaning or labeling operation.