Abstract: The present invention provides novel lentiviral packaging constructs that are useful for the establishment of stable packaging cell lines and producer cell lines. In particular, the present invention provides novel packaging cell lines that are capable of constitutively expressing high levels of lentiviral proteins.
Type:
Grant
Filed:
February 5, 2007
Date of Patent:
May 22, 2012
Assignee:
Novartis AG
Inventors:
Michael Kaleko, Tianci Luo, Ivan Plavec, Janet Lynn Douglas