Abstract: Crystalline form II of cabergoline, a pharmaceutical composition containing it and a process for its preparation are disclosed. The process may comprise crystallization from s solution of raw cabergoline in an organic solvent at low temperatures or submitting to a slurry procedure a mixture of cabergoline forms I and II in a solvent at a temperature below 30° C.

Abstract: A light transmitting panel of the type for connecting within a metal roofing system is provided. The light transmitting panel includes a translucent panel, a metal panel and a linear coefficient buffer therebetween to allow the repective panels to expand and contract with respect to the other without loss of containment or seal. The light transmitting panel is formed so as to substantially match the configuration and the strength characteristics of the roofing system into which it is installed.

Abstract: Compounds which are 3-arylsulfonyl-2-methyl propanoic acid derivatives of formula (I): wherein X is HO—NH— or HO—, R1 is selected from phenyl, 4-chlorophenyl, 4-florophenyl, 4-cyanophenyl, benzamido (i.e., —NH—CO-Ph) and benzamido substituted on the terminal phenyl ring by C1-C4 alkyl, fluoro, chloro, cyano or C1-4 alkoxy; R2 is selected from (a) —S—Ar or —S—CH2—Ar wherein Ar is an aromatic moiety; (b) —O—Ar wherein Ar is as defined above; (c) —S-Het or —S—CH2-Het wherein Het is a heterocyclic ring; and (d) 2,5-dioxo-1-imidazolidinyl or 2,4-dioxo-1-imidazolinyl; and the pharmaceutically acceptable salts thereof; have potent and selective inhibitory activity against matrix metalloproteinases (MMPs) and can thus be used in the treatment and prevention of diseases mediated by MMPs.

Abstract: A process for producing crystalline form I of cabergoline, which process comprises crystallization of the desired form from a toluene/diethyl ether mixture comprising raw cabergoline, followed by recovery and drying of the resulting crystals. A new solvate form V of cabergoline, useful as an intermediate, is also provided.

Abstract: Compounds which are 4,5,6,7-tetrahydroindazole derivative formula (1), wherein the dotted line (x) represents a single or double bond; n is 0 or 1; R1, R2 and R3 have the meanings reported in the description; Ra, R′a, Rb, R′b, Rc, R′c have the meanings reported in the description, also comprising that Ra and Rb together and/or Ra and Rc together form a N-alkylpiperydinyl ring with 1 to 6 carbon atoms in the alkyl chain or a phenyl ring; or pharmaceutically acceptable salts thereof, are useful for treating cell proliferative disorders and Alzheimer's disease.

Abstract: The present invention provides a non-evaporating lubricant and cleaner formulation that protects all types of film by forming a slick protective coating that reduces or eliminates dirt, scratches and static charges. An embodiment of the present invention comprises an organic mixture of greater than ninety-five percent (95%) aliphatic hydrocarbons. A preferred embodiment of the present invention comprises aliphatic petroleum naphtha, aliphatic petroleum distillates and petroleum base oil.

Abstract: Crystalline form VII of cabergoline, a pharmaceutical composition containing it and a process for its preparation are disclosed. The process may comprise a slurry procedure using form I or mixture of forms I and VII of cabergoline in a solvent at a temperature above 30° C.

Abstract: Crystalline form II of cabergoline, a pharmaceutical composition containing it and a process for its preparation are disclosed. The process may comprise crystallization from a solution of raw cabergoline in an organic solvent at low temperatures or submitting to a slurry procedure a mixture of cabergoline Forms I and II in a solvent at a temperature below about 30° C.

Abstract: The present invention relates in general to a method and apparatus for planning a pressure survey, and in particular, a method and apparatus for using a pressure survey tool so that the user may predict in advance the number of pressure tests needed to be performed in a pressure survey such that the results fall within a desired standard deviation of the pressure gradient. The present invention further relates in general to a method and apparatus for performing a pressure survey, and in particular, a process of measuring pressure gradient and standard deviation thereof for downhole fluid bearing formations using information collected from pressure survey apparatus such that the requisite amount of information is collected to ensure the measurements actually received are within the desired standard deviation of the pressure gradient.

Abstract: A process for producing a substantially dry polymer particle powder. A mixture of polymerization reagents is formed from a mixture of at least one monomer source and a solvent selected from the group consisting essentially of water and organic solvents and an initiator source. The mixture of polymerization reagents is sprayed into a heated, controlled atmosphere, forming droplets of the mixture which are allowed to fall through the heated, controlled atmosphere for a sufficient period of time to obtain a desired degree of polymerization. The solvent is continuously evacuated from the atmosphere during the polymerization process.

Abstract: A clamp for securing wire rope or other flexible cord with a high retention force. The clamp of the present invention has an outer housing with a gripping surface therein for securing wire rope or other flexible cord placed therein against the opposing gripping surface of a traveling block, gripping force being applied by rotation of a threaded member in threaded engagement with outer housing. Wire rope or other flexible cord is thereby gripped with significant control over axial alignment and without compressing segments of wire rope or flexible cord together.

Abstract: The vane actuator according to the present invention is capable of operating effectively at a working pressure greater than 100 psig. The vane actuator comprises a vane shaft rotatably extending through a casing and a vane disposed within the casing defining a first pressure chamber and a second pressure chamber therein. The casing includes stiffening members for resisting deflection of and maintaining an internal seal within the casing when exposed to a pressure of 150 psig. The stiffening member may be located in the range of about 10° and 20° on either side of a casing centerline to minimize deflection of the casing when exposed to a pressure force.

Abstract: This invention provides a method of making single-wall carbon nanotubes by laser vaporizing a mixture of carbon and one or more Group VIII transition metals. Single-wall carbon nanotubes preferentially form in the vapor and the one or more Group VIII transition metals catalyzed growth of the single-wall carbon nanotubes. In one embodiment of the invention, one or more single-wall carbon nanotubes are fixed in a high temperature zone so that the one or more Group VIII transition metals catalyze further growth of the single-wall carbon nanotube that is maintained in the high temperature zone. In another embodiment, two separate laser pulses are utilized with the second pulse timed to be absorbed by the vapor created by the first pulse.

Abstract: The invention pertains to an apparatus for measuring a foot's length and width to correspond to a shoe size and a method to eliminate multiplexers and demultiplexers in circuits. The apparatus is a low profile self-contained apparatus comprising a transducing medium, a microcontroller, a reference impedance element, a signal amplifier, an analog to digital conversion circuit, and a display to generate and display foot sizing data. A microcontroller unit ?is connected directly to the hybrid multiplexing circuit which! contains algorithms which solve a set of linear equations to indirectly determine the electronic image of a foot. The shoe size is then calculated using a sizing algorithm and then displayed on a display which is connected to the output of the microcontroller unit.