Abstract: The present invention provides effective new methods and materials for maxillofacial bone augmentation, particularly alveolar ridge augmentation, that are free of problems associated with prior art methods. In one embodiment, these materials include human recombinant platelet derived growth factor (rhPDGF-BB) and a biocompatible matrix. In another embodiment, these materials include rhPDGF-BB, a deproteinized bone block or calcium phosphate, and a bioresorbable membrane. The use of these materials in the present method is effective in regenerating maxillofacial bones and facilitating achievement of stable osseointegrated implants. The mandible and maxilla are preferred bones for augmentation, and enhancement of the alveolar ridge is a preferred embodiment of the present invention.
Type:
Grant
Filed:
November 17, 2006
Date of Patent:
February 14, 2012
Assignee:
BioMimetic Therapeutics, Inc.
Inventors:
Samuel E. Lynch, Myron Nevins, Massimo Simion
Abstract: The present invention provides compositions and methods for facilitating fusion of bones in a joint. The present invention provides compositions and methods for promoting fusion of bones in arthrodetic procedures. In one embodiment, a method of performing an arthrodetic procedure comprises providing a composition comprising PDGF disposed in a biocompatible matrix and applying the composition to a site of desired bone fusion in a joint.
Abstract: An external fixator for securing two or more bone elements. The external fixator includes an elongated bar; a first carriage for mounting on the bar and for securement to a first bone element; a second carriage for mounting on the bar and for securement to a second bone element; and a drive mechanism for driving the first and second carriages along the length of the bar independent of one another.
Abstract: A method for attaching an applique panel to a support surface comprising securing a threaded stud to said support surface; placing a centering washer over said threaded stud such that said stud extends through the eyelet in said centering washer, and at least a portion of said centering washing is flush with said support surface; placing a hollow cone over said stud; placing an applique panel having an opening therein over the apex of said hollow cone such that said stud extends through said opening in said panel; placing an upper washer over said applique panel such that said stud extends through the eyelet in said upper washer; and placing a nut over the top of said threaded stud and rotating said nut thereby connecting and securing said upper washer, said applique panel, said hollow cone and said centering washer to said support surface.
Abstract: The disclosure herein describes an apparatus for laying an adhesive strip along the peripheral edges of a glass sheet positioned on a work table with a view to forming a double-glazed insulated glass panel. The apparatus comprises a handle with a housing mounted at one end thereof and includes therein a series of rollers for positioning and laying the adhesive strip on the glass sheet. A third roller, whose axis is perpendicular to the axis of each of the strip-laying rollers, applies pressure to the strip being laid.