Abstract: (1-Oxo-7,8-disubstituted-1,2,3,4-tetrahydro-6-naphthyloxy)- and (3,4-disubstituted-5-oxo-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yloxy)ac etic acids, their carboxylate salts, and the amide and 5-tetrazole derivatives thereof are active as diuretic and saluretic agents, which also have uricosuric activity.
Type:
Grant
Filed:
October 12, 1973
Date of Patent:
January 18, 1977
Assignee:
Merck & Co., Inc.
Inventors:
Otto W. Woltersdorf, Jr., Edward J. Cragoe, Jr., Everett M. Schultz, Gerald E. Stokker
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