Abstract: Substituted 4-quinoline-carboxylic acids useful in the treatment of arthritis and inhibition of progressive joint deterioration are disclosed together with methods of use and synthesis thereof.
Type:
Grant
Filed:
August 31, 1987
Date of Patent:
July 11, 1989
Assignee:
American Cyanamid Company
Inventors:
Leslie H. Sutherland, Adolph E. Sloboda, Ralph G. Child, John F. Poletto, Dennis W. Powell