Abstract: An enteral delivery universal port assembly fabricated from a first portion and a second portion of different materials. The first portion has a generally cylindrical side wall, an annular top surface and a corresponding annular bottom surface. The second portion has a central portion with a peripheral flange extending radially outward therefrom, and an annular portion positionable is superposed adjacent relationship to the annular bottom surface. Extending upwardly from the surface of the central portion are first and second projections, the first projection having a base which is a spikable membrane and the second projection being associated with filter means which allow air to enter the enteral nutritional product container to which the enteral delivery universal port assembly is secured in its operative embodiment.
Type:
Grant
Filed:
January 17, 1989
Date of Patent:
August 28, 1990
Assignee:
Abbott Laboratories
Inventors:
Paul A. Pezzoli, Gary N. Smith, Jerold Montgomery
Abstract: A closure containing an internalized microbial filter for use in enteral delivery set assemblies. The closure comprises a generally cylindrical side wall, a planar top surface having first and second projections, the first projection being associated with the spikable membrane while the second projection is associated with a filter and with means to limit air access to the filter. The closure also includes a bottom surface having an aperture which extends through the closure to the top surface thereof with the filter being secured to the bottom surface and extending across the opening of the aperture.
Type:
Grant
Filed:
January 19, 1989
Date of Patent:
June 19, 1990
Assignee:
Abbott Laboratories
Inventors:
Paul A. Pezzoli, James Renick, Gary N. Smith, Jerold W. Montgomery, David Hofferbert, Mark Larkin
Abstract: Disclosed are ultrafiltration processes for the enrichment and concentration of selected proteins from protein conaining fluids. Illustratively, IgG is concentrated from whey by means of multiple ultrafiltration "passes", using a metallic oxide ultrafiltration membrane, which are characterized by differing pH's.
Type:
Grant
Filed:
October 12, 1988
Date of Patent:
January 30, 1990
Assignee:
Abbott Laboratories
Inventors:
Christopher T. Cordle, Larry G. Criswell, Ronald L. Thomas
Abstract: An expedited process for the dispersion and neutralization of acid caseins in the manufacture of liquid caseinate that drastically reduces time and cost variables and allows for in-house production of caseinate. The process comprises the initial addition of a solubilizing agent (i.e. citrate) to an aqueous solution with a temperature of about 120.degree. F. to about 165.degree. F. prior to the addition of casein and a neutralizing agent. This process achieves a pH-perfect, soluble caseinate product in the form of a ready-to-use liquid or powdered caseinate.
Abstract: A composition, device and method for determining the presence of a reducing agent, such as ascorbic acid, in a test sample are disclosed. The composition comprises certain thiazine and oxazine compounds which, in their oxidized state, are colored, but which become colorless when reduced by a reducing agent. The device comprises a carrier matrix incorporated with the composition, and the method comprises contacting a test sample with the composition device and observing any detectable response such as a color change.
Type:
Grant
Filed:
August 11, 1977
Date of Patent:
February 27, 1979
Assignee:
Miles Laboratories, Inc.
Inventors:
David A. N. Morris, Patricia A. Rupchock, Mark T. Skarstedt
Abstract: A method and device for determining the specific gravity or osmolality of a liquid containing a nonionic, ionizable solute are disclosed. The method comprises contacting the liquid with an ionizing agent, thus converting the solute to ionized species in the liquid, and contacting the liquid with test means capable of producing a detectable response, such as a color response, dependent upon the specific gravity or osmolality of the ionized liquid. The composition comprises an ionizing agent capable, upon contact with the liquid, of ionizing the solute therein, and a test means capable, upon contacting the liquid containing the solute in ionized form, of producing a detectable response which is a function of the specific gravity or osmolality of the liquid. The device comprises a carrier matrix incorporated with the test means and the ionizing agent.
Type:
Grant
Filed:
August 23, 1976
Date of Patent:
August 22, 1978
Assignee:
Miles Laboratories, Inc.
Inventors:
Sisto Nicholas Stiso, Chester L. Sutula
Abstract: A test composition is disclosed which is useful in determining the presence of a peroxidatively active substance, such as hemoglobin, in a test sample. The composition comprises an organic hydroperoxide, an indicator capable of producing a detectable response in the presence of a peroxide, and a diluent having the structure ##STR1## IN WHICH R.sub.1 and R.sub.2, same or different, are hydrogen, alkyl or alkoxy having 1 to about 6 carbon atoms, or aryl. The method comprises preparing the test composition and incorporating it with a carrier matrix.