Abstract: Improved solvent suppression in NMR data is achieved using pulse sequences wherein each of a series of selective excitation pulses are followed by a magnetic gradient pulse and a delay, where the magnetic gradient pulse amplitudes monotonically decrease by a selected fraction of the preceeding gradient pulse. Decoupling a second nucleus during selective excitation pulses has been shown to be efficacious for suppression of organic solvents.
Type:
Grant
Filed:
December 23, 1996
Date of Patent:
December 8, 1998
Assignee:
Varian Associates, Inc.
Inventors:
Stephen H. Smallcombe, Steven L. Patt, Paul A. Keifer