Patents Represented by Attorney Edward R. Gates
  • Patent number: 5364783
    Abstract: Retroviruses are used as genetic tools to isolate transcriptionally active chromosomal regions. The retroviruses have a promoterless protein coding sequence located in U3 or U5. The retroviruses may be used to infect cells under conditions which permit selection for instances when the retrovirus integrates in close proximity to and under the control of a cellular promoter. The promoter and its associated gene then may be identified and isolated. In this manner, the retroviruses function as promoter-traps. Related methods and products including vectors, kits and assays provided.
    Type: Grant
    Filed: May 14, 1990
    Date of Patent: November 15, 1994
    Assignee: Massachusetts Institute of Technology
    Inventors: H. Earl Ruley, Harold von Melchner
  • Patent number: 5139951
    Abstract: A tissue or cell growth device is described for placement within a well of a cluster dish. The device has a cell or tissue retention element detachably attached to a hanger. The hanger preferably has openings allowing access to the well without removal of the member and is capable of positioning the cell or tissue retention element a preselected distance relative to the hanger. Also described are various embodiments of the device having differently shaped hangers and the combination of the device and a cluster dish.
    Type: Grant
    Filed: October 10, 1990
    Date of Patent: August 18, 1992
    Assignee: Costar Corporation
    Inventors: David Butz, George Lyman, David Root, Gregory Mathus
  • Patent number: 5116009
    Abstract: A chandelier having a frame for supporting ornaments with loop shafts attached thereto provides a frame member having a predetermined thickness and a width between an inner edge and an outer edge. An ornament shaft that terminates in a loop has segments that engage a width defining edges of the frame member while the ornament is positioned in a vertical hanging orientation. The ornament further includes an opening defined by the shaft and a portion of the loop that is constructed and arranged so that the frame member may be engaged with and disengaged from the loop only through the opening and only by first rotating the shaft substantially out of the vertical orientation. The loop is further constructed and arranged so that substantially vertical displacement is prevented. The opening may be defined by an end of the loop and the shaft and the frame member may include one or more formations or indentations having a width less than the width of adjacent sections for supporting the loop.
    Type: Grant
    Filed: May 28, 1991
    Date of Patent: May 26, 1992
    Assignee: A. Schonbek & Co., Inc.
    Inventor: Georg Bayer
  • Patent number: 5116483
    Abstract: The invention provides methods and devices for conducting affinity electrophoresis and for characterizing, identifying, selecting, separating and/or isolating molecules based upon affinity. Acceptor molecules are dispersed in discrete lanes within a gel and test molecules are electrophoresed simultaneously through the lanes. Therapeutics may be screened, heterogeneous mixes may be separated and affinity equilibrium constants determined. Special combs and casting trays for forming gels also are provided, as well as the gels formed thereby. An electrophoresis box also is provided.
    Type: Grant
    Filed: September 21, 1990
    Date of Patent: May 26, 1992
    Assignee: Massachusetts Institute of Technology
    Inventor: Arthur D. Lander
  • Patent number: 4930020
    Abstract: A photographic image is prepared for facsimile transmission by photocopying the photographic image onto a sheet of paper through a partially transparent screen. The screen may comprise a plurality of spaced dots on a sheet in which one of the sheet and dots are transparent and the other opaque to light transmission whereby the photocopy has reproduced on it the picture and the pattern of the dots with either the dots or the spaces between the dots forming the image of the picture.
    Type: Grant
    Filed: December 29, 1986
    Date of Patent: May 29, 1990
    Inventor: James F. Martin
  • Patent number: D326173
    Type: Grant
    Filed: September 27, 1990
    Date of Patent: May 12, 1992
    Inventor: Dixon Newbold
  • Patent number: D358123
    Type: Grant
    Filed: August 3, 1992
    Date of Patent: May 9, 1995
    Assignee: Bell Sports, Inc.
    Inventors: Dixon Newbold, Ian Gilley