Abstract: A method of treating rheumatoid arthritis comprising administering human Interleukin-4 (IL-4) to an individual afflicted with the disease. The IL-4 is administered with a pharmaceutically acceptable carrier in a dose ranging from 1 .mu.g to 100 mg.
Type:
Grant
Filed:
June 6, 1995
Date of Patent:
September 14, 1999
Assignee:
Schering Corporation
Inventors:
Frank Lee, Takashi Yokota, Ken-ichi Arai, Timothy Mosmann, Donna Rennick
Abstract: Monoclonal antibodies are provided which are specific for human interleukin-4. Kits and methods are also provided for detecting, measuring and immunopurifying human interleukin-4.
Type:
Grant
Filed:
December 12, 1994
Date of Patent:
June 15, 1999
Assignee:
Schering Corporation
Inventors:
John S. Abrams, Isabelle Chretien, Frank D. Lee