Patents Represented by Attorney Edwin P. Ching

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  • Method for raising or isolating an antibody to DCRS5
    Patent number: 7749718
    Abstract: Nucleic acids encoding mammalian, e.g., primate, receptors, purified receptor proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are described.
    Type: Grant
    Filed: July 28, 2008
    Date of Patent: July 6, 2010
    Assignee: Schering Corporation
    Inventors: Madaline Chirica, Robert A. Kastelein, Kevin W. Moore, Christi L. Parham
  • IL-1-like cytokine
    Patent number: 7705128
    Abstract: Nucleic acids encoding mammalian, e.g., primate, IL-1?, purified IL-1? polypeptides and fragments thereof. Binding proteins, e.g., antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Grant
    Filed: July 1, 2008
    Date of Patent: April 27, 2010
    Assignee: Schering Corporation
    Inventor: Jacqueline C. Timans
  • Nucleic acids encoding DCRS5
    Patent number: 7510853
    Abstract: Nucleic acids encoding mammalian, e.g., primate, receptors, purified receptor proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are described.
    Type: Grant
    Filed: September 18, 2003
    Date of Patent: March 31, 2009
    Assignee: Schering Corporation
    Inventors: Madaline Chirica, Robert A. Kastelein, Kevin W. Moore, Christi L. Parham
  • C23 Polypeptides
    Patent number: 7482426
    Abstract: Nucleic acids encoding a new family of small cysteine rich soluble proteins, from a mammal, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
    Type: Grant
    Filed: September 18, 2002
    Date of Patent: January 27, 2009
    Assignee: Schering Corporation
    Inventors: Karin Franz-Bacon, Daniel M. Gorman, Terrill K. McClanahan
  • Antibodies binding the TNF related protein, TNF-Y
    Patent number: 7427668
    Abstract: Nucleic acids encoding mammalian, e.g., primate or rodent, genes, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Grant
    Filed: March 25, 2005
    Date of Patent: September 23, 2008
    Assignee: Schering Corporation
    Inventor: Daniel M. Gorman
  • Mammalian receptor protein DCRS5;methods of treatment
    Patent number: 7422743
    Abstract: Nucleic acids encoding mammalian, e.g., primate, receptors, purified receptor proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are described.
    Type: Grant
    Filed: November 21, 2003
    Date of Patent: September 9, 2008
    Assignee: Schering Corporation
    Inventors: Madaline Chirica, Robert A. Kastelein, Kevin W. Moore, Christi L. Parham
  • DCRS5 polypeptides
    Patent number: 7411041
    Abstract: Nucleic acids encoding mammalian, e.g., primate, receptors, purified receptor proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are described.
    Type: Grant
    Filed: September 18, 2003
    Date of Patent: August 12, 2008
    Assignee: Schering Corporation
    Inventors: Madaline Chirica, Robert A. Kastelein, Kevin W. Moore, Christi L. Parham
  • IL-1-like cytokine antibodies
    Patent number: 7393530
    Abstract: Nucleic acids encoding mammalian, e.g., primate, IL-1?, purified IL-1? polypeptides and fragments thereof. Binding proteins, e.g., antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Grant
    Filed: July 7, 2006
    Date of Patent: July 1, 2008
    Assignee: Schering Corporation
    Inventor: Jacqueline C. Timans
  • Mammalian cytokine complexes
    Patent number: 7390481
    Abstract: Purified genes encoding cytokine from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using said reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: February 11, 2004
    Date of Patent: June 24, 2008
    Assignee: Schering Corporation
    Inventors: Birgit Oppmann, Jacqueline C. Timans, Robert A. Kastelein, J. Fernando Bazan
  • DIRS1 antibodies
    Patent number: 7342103
    Abstract: The present invention provides nucleic acids encoding mammalian, e.g., primate or rodent receptors, purified receptor proteins and fragments thereof, and antibodies against these receptor proteins. Methods of using these compositions for both diagnostic and therapeutic utilities are also provided.
    Type: Grant
    Filed: April 10, 2003
    Date of Patent: March 11, 2008
    Assignee: Schering Corporation
    Inventors: Christi L. Parham, Kevin W. Moore, Nicholas J. Murgolo, J. Fernando Bazan
  • MDL-1 polypeptides
    Patent number: 7332574
    Abstract: The purification and isolation of various genes which encode mammalian cell surface polypeptides. Nucleic acids, proteins, antibodies, and other reagents useful in modulating development of cells, e.g., lymphoid and myeloid, are provided, along with methods for their use.
    Type: Grant
    Filed: February 10, 2004
    Date of Patent: February 19, 2008
    Assignee: Schering Corporation
    Inventors: Alexander B. H. Bakker, Joseph H. Phillips, Lewis L. Lanier
  • Binding compounds to DAP12 proteins
    Patent number: 7319140
    Abstract: The purification and isolation of various genes which encode mammalian cell surface polypeptides. Nucleic acids, proteins, antibodies, and other reagents useful in modulating development of cells, e.g., lymphoid and myeloid, are provided, along with methods for their use.
    Type: Grant
    Filed: February 10, 2004
    Date of Patent: January 15, 2008
    Assignee: Schering Corporation
    Inventors: Alexander B. H. Bakker, Joseph H. Phillips, Lewis L. Lanier
  • IL-1-like cytokine antibodies
    Patent number: 7270816
    Abstract: Nucleic acids encoding mammalian, e.g., primate, IL-1?, purified IL-1? polypeptides and fragments thereof. Binding proteins, e.g., antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Grant
    Filed: October 27, 2003
    Date of Patent: September 18, 2007
    Assignee: Schering Corporation
    Inventor: Jacqueline C. Timans
  • AK155 polypeptides
    Patent number: 7241438
    Abstract: Purified genes encoding a cytokine from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using said reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: August 10, 2004
    Date of Patent: July 10, 2007
    Assignee: Schering Corporation
    Inventors: Rene De Waal Malefyt, Helmut Fickenscher, Bernhard Fleckenstein, Andrea Knappe
  • Mammalian genes; related reagents and methods
    Patent number: 7183382
    Abstract: Purified genes encoding cytokine from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using said reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: February 27, 2003
    Date of Patent: February 27, 2007
    Assignee: Schering Corporation
    Inventors: Birgit Oppmann, Rene De Waal Malefyt, Donna M. Rennick, Robert A. Kastelein, Maria T. Wiekowski, Sergio A. Lira, Satwant K. Narula
  • Regulatory T cells; methods
    Patent number: 7122340
    Abstract: Methods for increasing yields of regulatory T cells, useful, e.g., in transplantation contexts. Use of antigen presenting cells and anti-CD28 are also described.
    Type: Grant
    Filed: October 14, 2003
    Date of Patent: October 17, 2006
    Assignee: Schering Corporation
    Inventors: Franck J. Barrat, Pieter Andre Boonstra, Huub Savelkoul, Rene de Waal Malefyt, Anne O'Garra
  • Polypeptides of an IL-1-like cytokine
    Patent number: 7108850
    Abstract: Nucleic acids encoding mammalian, e.g., primate, IL-1?, purified IL-1? polypeptides and fragments thereof. Binding proteins, e.g., antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Grant
    Filed: October 27, 2003
    Date of Patent: September 19, 2006
    Assignee: Schering Corporation
    Inventor: Jacqueline C. Timans
  • Mammalian cell surface antigens; related reagents
    Patent number: 7063841
    Abstract: Purified genes encoding a T cell surface antigen from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this antigen are provided. Methods of using said reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: December 23, 2002
    Date of Patent: June 20, 2006
    Assignee: Schering Corporation
    Inventors: Daniel E. Gorman, Jeanine D. Mattson
  • Mammalian cell surface antigens; related reagents
    Patent number: 7025962
    Abstract: Purified genes encoding a T cell surface antigen from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this antigen are provided. Methods of using said reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: April 10, 2000
    Date of Patent: April 11, 2006
    Assignee: Schering Corporation
    Inventors: Daniel M. Gorman, Troy D. Randall, Albert Zlotnik
  • Purified mammalian cytokines; related reagents and methods
    Patent number: 7005501
    Abstract: CTLA-8 related antigens from mammals, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding said antigens. Methods of using said reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: February 14, 2003
    Date of Patent: February 28, 2006
    Assignee: Schering Corporation
    Inventors: Daniel M. Gorman, J. Fernando Bazan, Robert A. Kastelein, Gerard Zurawski