Patents Represented by Attorney, Agent or Law Firm Elias J. Lambris
  • Patent number: 6780629
    Abstract: The present invention relates to subtilase enzymes of the I-S1 and I-S2 sub-groups having an additional amino acid in the active site loop (c) region from positions 125 to 132. The variant subtilases of the present invention exhibit improved wash performance in a detergent in comparison to its parent enzyme.
    Type: Grant
    Filed: September 13, 2002
    Date of Patent: August 24, 2004
    Assignee: Novozymes A/S
    Inventors: Peter Kamp Hansen, Peter Bauditz, Frank Mikkelsen, Kim Vilbour Andersen, Carsten Andersen, Mads Norregaard-Madsen
  • Patent number: 6720174
    Abstract: This invention relates to improved phytases, preferably phytases of an increased thermostability, and a process of producing them. In particular, stabilizing amino acid mutations are introduced into a homologous protein, or the active site of a phytase is replaced in part or in toto. The corresponding DNA sequences and methods of preparing them are also disclosed, as are methods of producing the improved phytases, and the use thereof. Specific variants of Aspergillus fumigatus phytase and of consensus phytases are disclosed.
    Type: Grant
    Filed: January 20, 2000
    Date of Patent: April 13, 2004
    Assignees: Novozymes A/S, Roche Vitamins Inc.
    Inventor: Martin Lehmann
  • Patent number: 6632646
    Abstract: Enzymes produced by mutating the genes for a number of subtilisin proteases and expressing the mutated genes in suitable hosts are presented. The enzymes exhibit improved wash performance in comparison to their wild type parent enzymes. The enzymes are well-suited for use in detergent compositions.
    Type: Grant
    Filed: October 2, 2000
    Date of Patent: October 14, 2003
    Assignees: Novozymes A/S, Unilever PLC.
    Inventors: Dorrit Aaslyng, Sven Branner, Sven Hastrup, Leif Nørskov-Lauritsen, Ole Hvilsted Olsen, Merete Simonsen, Eric Casteleijn, Maarten Robert Egmond, Johan Haverkamp, John David Marugg, Arnoldus Theodorus Anthonius Mooren
  • Patent number: 6630340
    Abstract: The present invention relates to xyloglucanases belonging to family 5 of glycosyl hydrolases are derived from strains of Paenibacillus, especially from strains of Paenibacillus pabuli. The xyloglucanases show high performance in conventional liquid detergent compositions.
    Type: Grant
    Filed: March 1, 2001
    Date of Patent: October 7, 2003
    Assignee: Novozymes A/S
    Inventors: Reinhard Wilting, Mads Eskelund Bjørnvad, Markus Sakari Kauppinen, Martin Schulein
  • Patent number: 6551635
    Abstract: The present invention relates to a process for producing cheese from enzyme-treated cheese milk, and the use of the resulting produced cheese as ingredient in food products. More particularly, the present invention relates to a process for producing cheese from cheese milk treated with a enzyme selected from the group of phospholipases, in particular phospholipase A1, A2 and B. Also, the present invention relates to a process for stabilizing the fat emulsion of a milk composition, e.g. cream, and the use of such stabilized milk composition, e.g. for the manufacturing of UHT-cream or cream liquor.
    Type: Grant
    Filed: March 1, 2002
    Date of Patent: April 22, 2003
    Assignee: Novozymes, A/S
    Inventor: Per Munk Nielsen
  • Patent number: 6506586
    Abstract: The present invention relates to isolated nucleic acid sequences encoding polypeptides having haloperoxidase activity. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences.
    Type: Grant
    Filed: April 11, 2001
    Date of Patent: January 14, 2003
    Assignees: Novozymes, A/S, Maxygen, Inc.
    Inventors: Palle Schneider, Steffen Danielsen
  • Patent number: 6284524
    Abstract: The present invention relates to microbial pectate lyases, more specifically to microbial enzymes exhibiting pectate lyase activity as their major enzymatic activity in the neutral and alkaline pH ranges, to a method of producing such an enzyme, and to methods for using such enzymes in the textile, detergent and cellulose fiber processing industries.
    Type: Grant
    Filed: April 11, 2000
    Date of Patent: September 4, 2001
    Assignee: Novozymes A/S
    Inventors: Lene Nonboe Andersen, Martin Schülein, Niels Erik Krebs Lange
  • Patent number: 5935987
    Abstract: Therapeutically effective amounts of a 3,4-diarylchroman can be administered transdermally by incorporation of the 3,4-diarylchroman in a matrix or liquid reservoir patch suitable for transdermal delivery, which matrix or liquid reservoir patch optionally contains hydrophobic and/or hydrophilic vehicle(s).
    Type: Grant
    Filed: November 18, 1997
    Date of Patent: August 10, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Svend Treppendahl, Klaus Snej Jensen, Scott E. McGraw, Helle Weibel
  • Patent number: 5916901
    Abstract: The present invention relates to novel N-substituted amino alcohols, amino acids and acid derivatives thereof in which a substituted alkyl chain forms part of the N-substituent or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation.
    Type: Grant
    Filed: May 15, 1998
    Date of Patent: June 29, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Rolf Hohlweg, Tine Krogh J.o slashed.rgensen, Knud Erik Andersen, Uffe Bang Olsen, Peter Madsen, Zdenek Polivka, Otylie Konigova, Frantisek Miksik, Martina Kovandova, Alexandra Silhankova, Karel Sindelar
  • Patent number: 5356517
    Abstract: Resin can be hydrolyzed enzymatically during the peroxy bleaching (e.g. with hydrogen peroxide) commonly used in pulp manufacture and the use of lipase in the manufacture of CTMP-fluff will afford several significant advantages, such as a pronounced reduction in fats, low time-consumption, since the process can be carried out in less than one calendar day, no losses in brightness or yield, or only marginal brightness and yield losses, and low handling costs. The enzyme treatment during bleaching necessitates little or no change of commonly used bleaching conditions. As a further advantage, the peroxy bleaching is mostly made at alkaline pH, whereby the liberated fatty acids remain ionized and can thus easily be removed from the pulp during subsequent washing.
    Type: Grant
    Filed: April 16, 1992
    Date of Patent: October 18, 1994
    Assignees: Novo Nordisk A/S, SCA Wifsta-Ostrand AB
    Inventors: Lars S. Pedersen, Steen Skjold-Jorgensen
  • Patent number: RE38507
    Abstract: The staling of leavened baked products such as bread is retarded by adding an enzyme with exoamylase activity to the flour or dough used for producing the baked product in question.
    Type: Grant
    Filed: June 28, 2002
    Date of Patent: April 27, 2004
    Assignee: Novozymes A/S
    Inventor: Tine Olesen