Abstract: The invention relates to a process of fermenting plant material in a fermentation medium into a fermentation product using a fermenting organism, wherein one or more aldehyde dehydrogenases are present in the fermentation medium.
Abstract: The present invention relates to polypeptides having cellobiohydrolase I activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides.
Type:
Grant
Filed:
June 18, 2010
Date of Patent:
December 25, 2012
Assignee:
Novozymes A/S
Inventors:
Lene Lange, Wenping Wu, Dominique Aubert, Sara Landvik, Kirk Matthew Schnorr, Ib Groth Clausen
Abstract: The present invention relates to a method of constructing a variant of a parent Termamyl-like alpha-amylase, which variant has alpha-amylase activity and at least one altered property as compared to the parent alpha-amylase, comprises i) analyzing the structure of the parent Termamyl-like alpha-amylase to identify at least one amino acid residue or at least one structural part of the Termamyl-like alpha-amylase structure, which amino acid residue or structural part is believed to be of relevance for altering the property of the parent Termamyl-like alpha-amylase (as evaluated on the basis of structural or functional considerations), ii) constructing a Termamyl-like alpha-amylase variant, which as compared to the parent Termamyl-like alpha-amylase, has been modified in the amino acid residue or structural part identified in i) so as to alter the property, and, optionally, iii) testing the resulting Termamyl-like alpha-amylase variant with respect to the property in question.
Type:
Grant
Filed:
June 16, 2011
Date of Patent:
December 4, 2012
Assignee:
Novozymes A/S
Inventors:
Allan Svendsen, Henrik Bisgard-Frantzen, Torben Vedel Borchert
Abstract: The present invention relates to isolated polypeptides having endoglucanase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
Type:
Grant
Filed:
April 25, 2011
Date of Patent:
November 13, 2012
Assignee:
Novozymes A/S
Inventors:
Katja Salomon Johansen, Keith Gibson, Preben Nielsen, Helle Outtrup
Abstract: The invention relates to a process of fermenting plant material in a fermentation medium into a fermentation product using a fermenting organism, wherein one or more carbonic anhydrases are present in the fermentation medium.
Abstract: The invention relates to a novel Termamyl-like alpha-amylase, and Termamyl-like alpha-amylases comprising mutations in two, three, four, five or six regions/positions. The variants have increased thermostability at acidic pH and/or at low Ca2+ concentrations (relative to the parent).
Type:
Grant
Filed:
June 29, 2009
Date of Patent:
September 11, 2012
Assignee:
Novozymes A/S
Inventors:
Allan Svendsen, Torben Vedel Borchert, Henrik Bisgard-Frantzen, Helle Outtrup, Bjarne Ronfeldt Nielsen, Vibeke Skovgaard Nielsen, Lisbeth Hedegaard
Abstract: The invention relates to a variant of a parent Termamyl-like alpha-amylase, which variant has alpha-amylase activity and exhibits an alteration in at least one of the following properties relative to the parent alpha-amylase: substrate specificity, substrate binding, substrate cleavage pattern, thermal stability, pH/activity profile, pH/stability profile, stability towards oxidation, Ca2+ dependency and specific activity.
Type:
Grant
Filed:
May 4, 2011
Date of Patent:
September 11, 2012
Assignee:
Novozymes A/S
Inventors:
Allan Svendsen, Torben Vedel Borchert, Henrik Bisgard-Frantzen
Abstract: The present invention relates to a hybrid enzyme comprising carbohydrate-binding module amino acid sequence and a fungal alpha-amylase amino acid sequence and to a variant of a fungal wild type enzyme comprising a carbohydrate-binding module and an alpha-amylase catalytic module. The invention also relates to the use of the hybrid enzyme or the variant in starch liquefaction.
Type:
Grant
Filed:
August 20, 2010
Date of Patent:
September 11, 2012
Assignees:
Novozyms A/S, Novozymes North America, Inc.
Inventors:
Hiroaki Udagawa, Rikako Taira, Shinobu Takagi, Carsten Hjort, Anders Vikso-Nielsen, Eric Allain, Shiro Fukuyama, Tomoko Matsui
Abstract: The invention relates to a process of fermenting plant material in a fermentation medium into a fermentation product using a fermenting organism, wherein increased levels of one or more pyrophosphatase enzymes are present in the fermentation medium.
Type:
Grant
Filed:
November 19, 2008
Date of Patent:
July 24, 2012
Assignee:
Novozymes North America, Inc.
Inventors:
Chee-Leong Soong, Jiyin Liu, Zhengfang Kang
Abstract: The invention relates to a variant of a parent fungal glucoamylase, which exhibits improved thermal stability and/or increased specific activity using saccharide substrates.
Abstract: The present invention relates to the use of isolated polypeptides as coccidiostats and/or histomonastats. An example of a polypeptide of the invention is the so-called L12 protein from Bacillus licheniformis ATCC 14580.
Abstract: The invention relates to an improved process of producing a fermentation product, such as ethanol, from starch-containing material using an increased dosage of alpha-amylase during liquefaction, which results in increased conversion of dextrins compared to conventional processes, and/or a reduced dosage of carbohydrate-generating enzyme during simultaneous saccharification and fermentation compared to a conventional process carried out at the same conditions. A process of the invention results in an increased yield. The invention also relates to an improved process of producing a fermentation product resulting in substantially the same yield as a conventional process, wherein reduced dosage of carbohydrate-source generating enzyme is used during simultaneous saccharification and fermentation.
Type:
Grant
Filed:
September 19, 2006
Date of Patent:
July 10, 2012
Assignee:
Novozymes North America, Inc.
Inventors:
George E. Gill, Billie Jean Savage, Swapnil Bhargava
Abstract: The present invention relates to phytases having at least 76% identity to a phytase derived from Hafnia alvei and comprises at least one modification in the amino acid sequence thereof. These phytase variants have modified, preferably improved, properties, such as, reduced protease sensibility, preferably they exhibit improved properties in respect of thermal performance, such as heat-stability (temperature stability, thermostability), steam stability, pelleting stability and/or temperature profile; and/or protease stability, in particular pepsin stability, pH profile, specific activity, substrate specificity, performance in animal feed (such as an improved release and/or degradation of phytate), susceptibility to glycation, and/or glycosylation pattern. The invention also relates to DNA encoding these phytases, methods of their production, as well as the use thereof, e.g., in animal feed and animal feed additives.
Type:
Grant
Filed:
September 28, 2009
Date of Patent:
June 26, 2012
Assignee:
Novozymes A/S
Inventors:
Soeren Flensted Lassen, Leonardo De Maria, Esben Peter Friis, Tomoko Matsui, Allan Noergaard, Lars Kobberoee Skov, Jesper Vind
Abstract: A method of forming localized variation of color density in the surface of a dyed cellulosic fabric with reducing back staining, with a composition comprising a cellulose having the amino acid sequence of SEQ ID NO: 2 or an amino acid sequence having at least 75% sequence identity with SEQ ID NO: 2 is provided. A method for biopolishing a cellulose-containing fabric by using the new endoglucanase is also provided.
Type:
Grant
Filed:
February 19, 2009
Date of Patent:
June 12, 2012
Assignee:
Novozymes A/S
Inventors:
Guifang Wu, Sarah Teter, Paul Harris, Weijian Lai
Abstract: The present invention relates to isolated polypeptides having antimicrobial activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
Abstract: The present invention relates to polypeptides having glucoamylase activity and isolated polynucleotides encoding said polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides. The invention also relates to the composition comprising a glucoamylase of the invention as well as the use such compositions for starch conversion processes, brewing, including processes for producing fermentation products or syrups.
Type:
Grant
Filed:
December 10, 2009
Date of Patent:
April 3, 2012
Assignees:
Novozymes A/S, Novozymes North America, Inc.
Inventors:
Hiroaki Udagawa, Sara Landvik, Michiko Ihara, Jiyin Liu, Chee Leong Soong, Eric Allain, Shiro Fukuyama
Abstract: The invention relates to a variant of a parent Termamyl-like alpha-amylase, which variant exhibits altered properties, in particular reduced capability of cleaving a substrate close to the branching point, and improved substrate specificity and/or improved specific activity relative to the parent alpha-amylase.
Type:
Grant
Filed:
November 23, 2010
Date of Patent:
February 28, 2012
Assignee:
Novozymes A/S
Inventors:
Carsten Andersen, Christel Thea Jorgensen, Henrik Bisgard-Frantzen, Allan Svendsen, Soren Kjaerulff
Abstract: The formation of acrylamide during heat treatment in the production of a food product is reduced by treating the raw material with an enzyme before the heat treatment. The enzyme is capable of reacting on asparagine or glutamine (optionally substituted) as a substrate or is a laccase or a peroxidase.
Type:
Grant
Filed:
December 7, 2007
Date of Patent:
February 28, 2012
Assignee:
Novozymes A/S
Inventors:
Gitte Budolfsen, Morten Tovborg Jensen, Hans Peter Heldt-Hansen, Mary Ann Stringer, Lene Lange