Patents Represented by Attorney Elie H. Gendloff, Esq.

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  • Polynucleotides comprising intercalating entities
    Patent number: 8334370
    Abstract: Provided are nucleic acid compositions modified with intercalating aromatic compounds attached directly or indirectly through a linker arm thereto. Modifications to the nucleotides or to the oligo- or polynucleotides involve the pentosyl moieties, the abasic moieties (without a base) and the base moieties. Useful property changes are effected and can be measured or detected when such modified nucleic acids compositions have hybridized specifically to target nucleic acids.
    Type: Grant
    Filed: October 5, 1992
    Date of Patent: December 18, 2012
    Assignee: Enzo Biochem, Inc.
    Inventors: Jannis Stavrianopoulos, Elazar Rabbani