Patents Represented by Attorney Elies J. Lambiris, Esq

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  • Insulin analogs having a modified B-chain
    Patent number: 5716927
    Abstract: Human insulin analogues having a positively charged amino acid residue, i.e. Lys or Arg, in position B28, further being modified in the C-terminal end of the B-chain from Phe.sup.B24 to the C-terminal amino acid residue and wherein A18, A21 and/or B3 is different from Asn as well as insulin preparations containing the human insulin analogues are provided.
    Type: Grant
    Filed: September 21, 1995
    Date of Patent: February 10, 1998
    Assignee: Novo Nordisk A/S
    Inventors: Per Balschmidt, Jens J.o slashed.rgen Veilgaard Brange