Patents Represented by Attorney Elins J. Lambiris

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  • Morphological mutants of filamentous fungi
    Patent number: 6066493
    Abstract: The present invention relates to methods of obtaining a mutant cell from a filamentous fungal parent cell, comprising: (a) obtaining mutant cells of the parent cell; (b) identifying the mutant cell which exhibits a more restricted colonial phenotype and/or a more extensive hyphal branching than the parent cell; and (c) identifying the mutant cell which has an improved property for production of a heterologous polypeptide than the parent cell, when the mutant and parent cells are cultured under the same conditions.
    Type: Grant
    Filed: March 13, 1997
    Date of Patent: May 23, 2000
    Assignee: Novo Nordisk Biotech, Inc.
    Inventors: Jeffrey R. Shuster, John C. Royer