Abstract: This invention is directed to implantable coils and, more particularly, to a coil implant having a stretch-resistant member internal to the coil. The implant of the invention is able to freely articulate and torque prior to delivery. Once delivered, the implant is no longer stretch resistant and is therefore able to substantially conform to the vascular site.

Abstract: A method of reducing blood flow within an aneurysm includes: injecting a contrast agent into a blood vessel including an aneurysm; deploying an occlusion device across the aneurysm; producing an image of the aneurysm including the contrast agent; and withdrawing the delivery device from the vessel after observing that the aneurysm has been obstructed by a desired amount. The image may be two-dimensional or three-dimensional. Observing that the aneurysm has been obstructed may include determining a degree of obstruction, for example by comparing an area or volume of the contrast agent in a first image and a second image. The desired amount may be a certain degree of obstruction, identification of a shape indicative of stasis such as a flat surface, an approximate hemisphere, a mushroom, or a crescent. If the occlusion device does not achieve the desired amount, a second occluding device may be deployed.

Abstract: A vaso-occlusive device is provided for reducing blood flow in a patient. The device can include a coil, a stretch resistant member, and a plurality of fibers. The coil can define a lumen and be sized for insertion to a point of use in a vascular network of the patient. The stretch resistant member can have a first end fixedly attached to the first end of the coil. Further, the plurality of fibers can be configured with each of the fibers in direct contact with the stretch resistant member.

Abstract: A catheter used for treatment of complex vasculature, such as a bifurcated aneurysm, is provided with an inflatable balloon at a distal portion thereof. The shape, location and material of the inflatable balloon are selected such that when inflated, the balloon conforms to the shape of the complex vasculature, or at least a portion thereof, without appreciably deforming the vessel walls. In this manner, the balloon can be used to control flow in the vasculature, for example occluding a selected branch of the vasculature during introduction of material in order concentrate the material and minimize its disbursement by blood flow.

Abstract: The invention, in one embodiment, is directed to a catheter for site-specific delivery of a therapeutic agent to a blood vessel of a patient. The catheter further includes an elongated shaft having at least one inner lumen, a distal end and a proximal end and proximal and distal vessel-conforming balloons where each is separately positionable and inflatable, and when inflated, substantially restricts blood flow in the vessel and creates a treatment window of a defined but variable length for delivery of the therapeutic agent. The catheter optionally includes at least one marker band adjacent to the proximal balloon and at least one marker band adjacent to the distal balloon. At least one lateral aperture positioned in the window is in fluid communication with a drug delivery conduit located within either the inner shaft or the outer shaft to provide a homogeneous concentration of the therapeutic agent to the window.

Abstract: Medical devices made at least in part of amorphous metals or alloys are provided. Certain embodiments include filters, stents, guidewires, snares, and coils comprised of amorphous metal. Methods of forming the medical devices, including methods of shape setting amorphous metals or alloys into components of medical devices are also provided. Methods of using amorphous metal medical devices are also provided.

Abstract: A device for the implantation of electrolytically severable occluding spirals in body cavities or blood vessels comprising a source of electrical power, a cathode, a catheter and an occluding spiral adapted to serve as an anode and able to slide in the catheter in the longitudinal direction, wherein the occluding spiral (3) is designed to be electrolytically corrodible at several spaced apart points so that when in contact with a body fluid one or more variably dimensioned lengths of the occluding spiral (3) may be severed by electrolysis.

Abstract: A system for recovery and reutilization of sterilant gas mixture from a sterilizer chamber includes a storage tank in gaseous communication with a sterilizer chamber via a gas recovery assembly, wherein after sterilization the gas recovery assembly evacuates the sterilant gas mixture to the storage recovery tank. The system also includes an inert purge gas supply adapted to supply a purge gas to the sterilizer chamber after the sterilant gas mixture is withdrawn to the storage recovery tank, wherein the gas recovery assembly evacuates an additional portion of the purge gas from the sterilizer chamber to the storage tank to enrich the gas mixture for later reutilization in subsequent sterilization cycles.

Abstract: A system for testing a negative pressure wound dressing, includes a simulated wound having a housing and a wound cavity within the housing, and having a shape and dimension representative of an actual wound type, a wound dressing positionable at least over the simulated wound, a negative pressure source in fluid communication with the wound cavity, at least one sensor adapted to record at least one parameter within the simulated wound, an air leak model including a valve in fluid communication with the wound cavity whereby opening of the valve simulates an air leak within the wound cavity, a fluid source in fluid communication with the wound cavity for delivering fluid to the wound cavity to simulate presence of exudates and a computer coupled to the at least one sensor for recording and analyzing data recorded by the at least one sensor to thereby providing an indication of functioning of the system.

Abstract: A composite wound dressing apparatus promotes healing of a wound via the use of a micropump system housed within a wound dressing member. The micropump system includes a miniature pump that applies a subatmospheric pressure to the wound to effectively draw wound fluid or exudate away from the wound bed without the need for an external vacuum source. Hence, the wound dressing and micropump system is portable which allows the patient mobility that is unavailable when an external vacuum source is used. The patient does not need to be constrained for any period of time while exudate is being removed from the wound.

Abstract: An apparatus for promoting the healing of a wound includes a pressure-sensitive adhesive disposed around a periphery of the wound, and a membrane layer in positioned over the wound with a lower surface in contact with the pressure-sensitive adhesive to form a substantially fluid-tight seal to define reservoir over the wound in which a negative pressure may be maintained. In fluid communication with the reservoir is a vacuum source suitable for providing an appropriate negative pressure to the reservoir to stimulate healing of the wound. A resilient member is placed over an upper surface of the membrane layer, and a compression member is configured to apply a compressive force to the resilient member. The resilient member distributes the compressive force to the membrane layer to reinforce the fluid tight-seal.

Abstract: A wound dressing includes one or more layers containing a first anti-microbial agent and/or at least one zinc-containing agent.

Abstract: A wound dressing apparatus for use in subatmospheric pressure therapy includes an outer member dimensioned for positioning relative to a wound bed and defining an internal reservoir, a port associated with the outer member and in communication with the internal reservoir for applying subatmospheric pressure to the internal reservoir to facilitate treatment of the wound bed and removal of fluid therefrom, an inner member at least partially positionable within the wound bed and confined within the outer member, and an adhesive agent in contact with a peripheral section of the outer member to facilitate attachment of the peripheral section to the periwound tissue. The adhesive agent is preferably substantially devoid of contact with the inner member. In one embodiment, a layer of adhesive material is disposed on the peripheral section of the outer member.

Abstract: A wound dressing includes one or more layers containing a first anti-microbial agent and at least one of: a chelating agent, and a second anti-microbial agent.

Abstract: A disposable elastomeric glove has a secondary cuff disposed distally of a primary cuff on a wrist region of the glove. The secondary cuff may be grasped by an opposite hand to safely remove the glove with the primary cuff in place to protect the skin on the wrist from contaminants on the opposite hand. The secondary cuff approximates the design of the primary cuff such that the removal process is similar to that of a conventional glove.

Abstract: A composite wound dressing apparatus promotes healing of a wound via the use of a micropump system housed within or above a wound dressing member. The micropump system includes a miniature pump that applies a subatmospheric pressure to the wound to effectively draw wound fluid or exudate away from the wound bed without the need for a cumbersome external vacuum source. Hence, the wound dressing and micropump system is portable which allows the patient mobility that is unavailable when an external vacuum source is used. The patient does not need to be constrained for any period of time while exudate is being removed from the wound.