Patents Represented by Attorney Ellen A. Kapinos

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  • Homogeneous erythropoietin compositions and methods of using same
    Patent number: 5322837
    Abstract: A method for purifying erythropoietin is described. The method comprises treating partially purifying erythropoietin by reverse phase high performance liquid chromatography to obtain homogeneous erythropoietin having a molecular weight of about 34,000 daltons on SDS PAGE and moving a single peak on reverse phase HPLC. The homogeneous erythropoietin protein preferably has a specific activity of at least 120,000 IU, more preferably at least 160,000 IU per absorbance unit at 280 nm.
    Type: Grant
    Filed: July 31, 1992
    Date of Patent: June 21, 1994
    Assignee: Genetics Institute, Inc.
    Inventors: Rodney M. Hewick, Jasbir S. Seenra