Patents Represented by Attorney Ellen Coletti

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  • Substituted diamine derivatives useful as motilin antagonists
    Patent number: 7112586
    Abstract: The present invention relates to novel substituted diamine derivatives for the formula wherein R1, R2, R3, R4, X1, X2, X3, X4, A, Y and n are as described in the specification, pharmaceutical compositions containing them and intermediates used in their manufacture. More particularly, the compounds of the invention are motilin receptor antagonists useful for the treatment of associated conditions and disorders such as gastrointestinal reflux disorders, eating disorders leading to obesity and irritable bowel syndrome.
    Type: Grant
    Filed: February 25, 2005
    Date of Patent: September 26, 2006
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Sigmond G. Johnson, Ralph A. Rivero