Patents Represented by Attorney Elliot N. Schubert

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  • Spirolactone for inhibiting the cardiotoxic effects of adriamycin
    Patent number: 4003996
    Abstract: The administration of aldosterone inhibitors of the spirolactone structural type prior to and during treatment with anti-neoplastic agents such as adriamycin results in retention of the desired activity of the latter substances while inhibiting their undesirable cardiotoxic properties.
    Type: Grant
    Filed: September 9, 1974
    Date of Patent: January 18, 1977
    Assignee: G. D. Searle & Co.
    Inventors: Raphael Pappo, Rothwell Polk
  • Interferon purification
    Patent number: 3975344
    Abstract: Interferon and interferon-like proteins isolated from animal cells are purified by means of zonal density gradient centrifugation.
    Type: Grant
    Filed: October 2, 1974
    Date of Patent: August 17, 1976
    Assignee: G. D. Searle & Co.
    Inventor: Alan Asher Schwartz
  • Vaccines against feline leukemia
    Patent number: 3966907
    Abstract: Vaccines affording protection against the diseases resulting from infection of cats with feline leukemia virus are produced from cells infected with that virus or from the virus alone.
    Type: Grant
    Filed: September 13, 1974
    Date of Patent: June 29, 1976
    Assignee: University of Glasgow
    Inventors: William Fleming Hoggan Jarrett, James Oswald Jarrett, Lindsay Joan Mackey
  • Total synthesis of 11-alkyl steroids
    Patent number: 3962291
    Abstract: A novel total synthesis of 11-alkyl steroids, utilizing readily available and inexpensive raw materials, is described. The resulting products are useful and novel pharmacological agents possessing, for example, selective hormonal properties.
    Type: Grant
    Filed: September 5, 1974
    Date of Patent: June 8, 1976
    Assignee: G. D. Searle & Co.
    Inventors: Robert B. Garland, Raphael Pappo
  • Polynucleotides of poly(5-hydroxycytidylic acids)
    Patent number: 3935185
    Abstract: Poly(5-hydroxycytidylic acids), produced by the enzymatic polymerization of 5-hydroxycytidylic acid, possess the ability to induce the production of interferon and, furthermore, exhibit anti-viral properties.
    Type: Grant
    Filed: March 28, 1974
    Date of Patent: January 27, 1976
    Assignee: G. D. Searle & Co.
    Inventors: David Wesley Hutchinson, Michael Anthony William Eaton
  • Mono- and dialkylated prostynoic acid derivatives
    Patent number: 3932496
    Abstract: Novel mono- and dialkylated prostynoic acid derivatives, prepared by condensation of a suitably substituted cyclopentene carboxylic acid or ester with a suitable organometallic alkynyl derivative, display valuable pharmacological properties. For example, they are potent inhibitors of gastric secretion.
    Type: Grant
    Filed: April 23, 1973
    Date of Patent: January 13, 1976
    Assignee: G. D. Searle & Co.
    Inventors: Christopher Jung, Raphael Pappo
  • Non-stinging wound dressing
    Patent number: 3932602
    Abstract: This invention is concerned with a non-stinging wound dressing. This wound dressing is characterized by plastics dissolved in a solvent system of stinging and non-stinging solvent, the combination of which provides a non-stinging solvent system with sufficient polarity to dissolve the plastic. This wound dressing is preferrably applied to wounds as an aerosol spray dressing containing bacteriostatic agents.
    Type: Grant
    Filed: December 13, 1973
    Date of Patent: January 13, 1976
    Assignee: Novitas Nuprot SA
    Inventor: Ulf Alan Sweger
  • Method for tranquilization without general depression
    Patent number: 3931411
    Abstract: The administration to mammals of prostaglandin PGA.sub.2, derivatives of PGA.sub.2, methyl ester of .omega.-homo PGE.sub.1 and compounds structurally related to prostaglandins, such as alkyl 11,15-dihydroxy-15-alkyl-9-oxoprost-13-ynates and 11-methyl-15-hydroxy-9-oxoprosta-5-cis-13-trans-dienoic acid results in a state of tranquilization as opposed to general depression.
    Type: Grant
    Filed: December 26, 1973
    Date of Patent: January 6, 1976
    Assignee: G. D. Searle & Co.
    Inventor: Walter Joseph Potts