Patents Represented by Attorney Emanuel
  • Patent number: 8335234
    Abstract: The present invention relates to the domain of control methods of a plurality of formatting equipment (FE1, FE2) of streams (TS) used as backup. The items of equipment receive the streams (TS) and send, to a modulator (MOD1), formatted streams (TS_SFN1, TS_SFN2) comprising a succession of blocks of packets called “megaframe” and megaframe initialization packets (MIP) used by the modulator (MOD1) to identify in time a megaframe (MFn) relatively to a time base (TB).
    Type: Grant
    Filed: October 23, 2009
    Date of Patent: December 18, 2012
    Inventors: Stéphane Fillod, Pascal Gravoille, Stéphane Guillemot
  • Patent number: 8306298
    Abstract: A method of and apparatus for viewing microscopic images include transmitting tiled microscopic images from a server to a client. The client assembles the tiled images into a seamless virtual slide or specimen image and provides tools for manipulating image magnification and viewpoint. The method and apparatus also provides a virtual multi-headed microscope function which allows scattered viewers to simultaneously view and interact with a coherent magnified microscopic image.
    Type: Grant
    Filed: December 21, 2010
    Date of Patent: November 6, 2012
    Assignee: Olympus America Inc.
    Inventors: James V. Bacus, James W. Bacus
  • Patent number: 8306300
    Abstract: A virtual microscope slide includes images of a specimen for a given level of optical magnification which are associated and stored in a data structure. The forming of the data structure having the multiple Z-plane images preferably includes automatically focusing at a principal reference focal plane and capturing and digitizing an optically magnified reference Z-image and then shifting the specimen relative to the lens system by a predetermined increment to capture and digitize another Z-plane image. Preferably, a multiple sequence of Z-plane images above and below the reference image and captured and digitized. For ease of retrieval and use, each reference image has its associated Z-plane images are formed in a stack that is sent over the Internet, or Intranet to a local computer storage for quick retrieval when a viewer wants to mimic a focusing up or down to better view a detail in an image.
    Type: Grant
    Filed: April 8, 2011
    Date of Patent: November 6, 2012
    Assignee: Olympus America Inc.
    Inventors: James V. Bacus, James W. Bacus
  • Patent number: 8248681
    Abstract: The present disclosure relates generally to polyaniline (PANI) materials capable of undergoing stable and reversible polyelectrochromic transitions between multiple oxidation states. More specifically, the embodiments described herein include novel PANI-PAAMPSA structures that are capable of undergoing stable and reversible transitions between the ES, LB and PB oxidation states. In some embodiments, the structures described are capable of undergoing stable transitions over a broad pH range. Also described herein are methods of preparing certain electrochromic structures.
    Type: Grant
    Filed: January 4, 2011
    Date of Patent: August 21, 2012
    Assignee: The Trustees of Princeton University
    Inventors: Yueh-Lin Loo, Joung Eun Yoo, Jacob Tarver
  • Patent number: 8247443
    Abstract: A novel small molecule antagonizes two types of acyl homoserine lactone receptors: membrane-bound and cytoplasmic. A focused library of analogs and derivatives of the original antagonist was synthesized. Analog and derivative molecules harbor a range of activities. The novel small molecule and most potent antagonist protects the eukaryote Caenorhabditis elegans from quorum-sensing-mediated killing by the bacterial pathogen Chromobacterium violaceum. The saving of C. elegans demonstrates the use of these molecules as small molecule antimicrobials.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: August 21, 2012
    Assignee: The Trustees of Princeton University
    Inventors: Bonnie L. Bassler, Lee R. Swem, Scott M. Ulrich, Colleen T. O'Loughlin
  • Patent number: 8093098
    Abstract: A method for enhancing electrical conductivity of a film which includes at least one conductive polymer. The method includes providing the film comprising the at least one conductive polymer and at least one polymer acid, agitating the film in at least one reagent; and, placing the film on a heated surface. The at least one reagent includes a reagent acid that is stronger than the polymer acid. The conductivity of the treated film is significantly greater than the conductivity of the untreated film.
    Type: Grant
    Filed: October 6, 2009
    Date of Patent: January 10, 2012
    Assignees: The Trustees of Princeton University, The Board of Regents, the University of Texas System
    Inventors: Yueh-Lin Loo, Joung Eun Yoo, Kwang Seok Lee
  • Patent number: 7578971
    Abstract: Compositions for CO2 detector solutions and rapid-response reversible dry surface CO2 detectors made from them are disclosed. The CO2 detector solutions generally comprise a poly(oxyethylene) based compound, a pH sensitive indicator dye, an organic solvent, a cationic phase transfer agent and an anionic base. However, minimally these detector solutions comprise a poly(oxyethylene) based compound, a pH sensitive indicating dye, an organic solvent and a base. The solutions were embedded onto a solid support made of polyethersulfone filter material in order to form rapid-response reversible dry surface CO2 detectors. Rapid-response reversible dry surface CO2 detectors are produced which function at rates in excess of 180 one-way color changes/minute when exposed to alternating 0% and 5% CO2 concentrations. A preferred embodiment using cationic methyltricaprylylammonium in conjunction with the phenoxide anion is substantially humidity resistant.
    Type: Grant
    Filed: March 23, 2005
    Date of Patent: August 25, 2009
    Assignee: Mercury Enterprises, Inc.
    Inventors: Jeffrey Bruce Ratner, David Matthew Green, Darrell Wayne Crick, Marc Edward Halpern
  • Patent number: 7422670
    Abstract: A gel and buffer system for gel electrophoresis wherein separation occurs at neutral pH.
    Type: Grant
    Filed: February 21, 2003
    Date of Patent: September 9, 2008
    Inventors: Timothy V Updyke, Sheldon C Engelhorn
  • Patent number: 7374518
    Abstract: The construction of a collapsible rotary torso exercise machine is disclosed. The machine's extended parts fold down and/or detach so that it may be stored in a small space. The machine is also lightweight and therefore portable. Three different types of resistance mechanism are specifically disclosed: 1) piston in cylinder resistance 2) friction resistance and 3) elastic member resistance. The collapsible rotary torso exercise machine preferably has variable resistance and for each type of resistance mechanism disclosed, a mechanism or method for varying the resistance is also disclosed.
    Type: Grant
    Filed: August 16, 2005
    Date of Patent: May 20, 2008
    Inventor: Jeffrey Bruce Ratner
  • Patent number: 7361260
    Abstract: The invention provides methods, apparatus and kits for integrally labeling polymeric gels, such as polyacrylamide and agarose gels, with indicia that can serve, inter alia, unambiguously to identify the individual gel, using polymeric film labeled with detectable indicia and coated with materials that bond to the gel matrix as the gel polymerizes.
    Type: Grant
    Filed: September 20, 2002
    Date of Patent: April 22, 2008
    Inventors: Joseph W Amshey, Allen Bautista
  • Patent number: 6733971
    Abstract: The present invention provides transcription factors associated with the hedgehog signaling pathway that are regulated by dephosphorylation by phosphatases. Hedgehog response elements (HRE) that interact with the dephosphorylated transcription factors are also provided as well as methods for identifying compounds that are phosphatase inhibitors. Methods of treating tumors in a subject by modulating the phosphorylation of the transcription factor are also included.
    Type: Grant
    Filed: August 21, 2001
    Date of Patent: May 11, 2004
    Assignees: Baylor College of Medicine, The Johns Hopkins University School of Medicine
    Inventors: Philip A. Beachy, Ming-Jer Tsai, Sophia Tsai, Venkatesh Krishnan, Chien-Huan Chen
  • Patent number: 6720145
    Abstract: Disclosed is a method for removing polynucleotide from the skin. This polynucleotide can be used to detect dermatitis and distinguish an irritant reaction from an allergic reaction by characterizing the polynucleotide according to the polypeptide which it encodes. Additionally, provided are methods for non-invasive isolation of samples from the skin as well as kits for use in the methods provided herein.
    Type: Grant
    Filed: September 28, 2001
    Date of Patent: April 13, 2004
    Assignee: Dermtech International
    Inventors: Lawrence A. Rheins, Vera B. Morhenn
  • Patent number: 6709818
    Abstract: Provided are methods and compositions useful for the diagnosis, prognosis and treatment of hepatic cellular proliferative disorders. The methods include the modulation or analysis of hypemethylated glutathione-S-transferase nuleic acid sequence in hepatic samples and biological fluids.
    Type: Grant
    Filed: October 12, 2000
    Date of Patent: March 23, 2004
    Assignee: The Johns Hopkins University School of Medicine
    Inventors: William G. Nelson, Xiaohui Lin, Julia C. Tchou, Jila Bakker
  • Patent number: 6635480
    Abstract: Growth differentiation factor, Lefty-2, is disclosed along with its polynucleotide sequence and amino acid sequence. Also disclosed are diagnostic and therapeutic methods of using the Lefty-2 polypeptide and polynucleotide sequences.
    Type: Grant
    Filed: April 14, 2000
    Date of Patent: October 21, 2003
    Assignee: The Johns Hopkins University School of Medicine
    Inventors: Se-Jin Lee, Thanh Huynh, Suzanne Sebald
  • Patent number: 6579704
    Abstract: The present invention relates to a method for sequencing nucleic acids. In particular, such method includes incorporating certain modified nucleotides referred to as Simtides into nucleic acid strands. These Simtides are complexes comprising a nucleotide base (or analog thereof), a linker, and a label capable of generating a detectable signal for sequencing. A Simtide may be incorporated into a sequencing fragment as a primer component, as a chain elongator, or as a chain terminator.
    Type: Grant
    Filed: May 8, 2001
    Date of Patent: June 17, 2003
    Assignee: Invitrogen Corporation
    Inventor: Jay M. Short
  • Patent number: 6562567
    Abstract: Disclosed is a method of detecting specific nucleic acids using an oligonucleotide linked to a cleavable tag. The presence of a specific nucleic acid in a population of nucleic acids is determined by hybridizing an oligonucleotide containing the tag to a population of nucleic acids, separating hybridizing bound oligonucleotides, and then removing and identifying the tag. Also provided are compositions and kits comprising oligonucleotides linked to a cleavable tag.
    Type: Grant
    Filed: January 27, 1999
    Date of Patent: May 13, 2003
    Assignee: California Institute of Technology
    Inventor: Barbara J. Wold
  • Patent number: 6544738
    Abstract: Disclosed is a method of detecting specific nucleic acids using an oligonucleotide linked to a cleavable tag. The presence of a specific nucleic acid in a population of nucleic acids is determined by hybridizing an oligonucleotide containing the tag to a population of nucleic acids, separating hybridizing bound oligonucleotides, and then removing and identifying the tag. Also provided are compositions and kits comprising oligonucleotides linked to a cleavable tag.
    Type: Grant
    Filed: April 25, 2000
    Date of Patent: April 8, 2003
    Assignee: California Institute of Technology
    Inventor: Barbara J. Wold
  • Patent number: 6115183
    Abstract: The disclosure relates to a device for illumination of a screen, notably a liquid-crystal screen. It includes a light integrator that receives a light beam from a source and outputs an illuminating beam for the screen. The light integrator makes use of lenses, but has no lenses in the parts of the beam where the energy flux is weak, which enables more uniform illumination of the screen. To improve the contrast of the illumination of the liquid-crystal screen, the whole illuminating beam is directed onto the screen at an angle to the optical axis of the system. The invention is applicable to liquid-crystal screens.
    Type: Grant
    Filed: April 16, 1996
    Date of Patent: September 5, 2000
    Assignee: Thomson multimedia S.A.
    Inventors: Khaled Sarayeddine, Eric Marcellin-Dibon, Valtor Drazic
  • Patent number: 6097442
    Abstract: A method and apparatus for reformatting auxiliary information such as closed caption text that is extracted from a television signal. The apparatus reformats the text by removing redundant spaces, reorganizing the text to fit into an arbitrary sized closed caption window, converting any closed caption display mode (e.g., pop on, paint on or roll up) into a modified roll on display, and inserting speaker identifier prompts into the caption.
    Type: Grant
    Filed: December 19, 1996
    Date of Patent: August 1, 2000
    Assignee: Thomson Consumer Electronics, Inc.
    Inventors: Mark Francis Rumreich, Mark Robert Zukas
  • Patent number: 6091818
    Abstract: The invention relates to a conditional access system making it possible for a service provider to supply his services solely to users having acquired entitlements to these services.The services supplied by a service provider consist of an item scrambled by control words. To keep these control words secret, they are supplied in messages (MEC) after having been encrypted with an encryption algorithm with key K.According to the invention, one and the same message (MEC) contains the same control word (Cwi) encrypted several times, each encryption (E(Cwi)Kj) of the control word depending on a different encryption key (Kj).The invention applies to any type of conditional access system, be this system either of "off-line" or "on-line" type.
    Type: Grant
    Filed: July 28, 1997
    Date of Patent: July 18, 2000
    Assignee: Thomson multimedia, S.A.
    Inventors: Arnaldo Campinos, Jean-Bernard Fischer