Patents Represented by Attorney Emily Homes

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  • Human mutant tissue factor compositions useful as tissue factor antagonists
    Patent number: 5994296
    Abstract: The present invention describes a mutant human tissue factor protein which binds functional Factor VII/VIIa but is substantially free of functional procoagulant cofactor activity, and compositions containing the mutant protein. Also disclosed are methods for using the mutant human tissue factor proteins, and recombinant DNA vectors for expressing the protein.
    Type: Grant
    Filed: March 5, 1998
    Date of Patent: November 30, 1999
    Assignee: The Scripps Research Institute
    Inventors: Wolfram Ruf, Thomas S. Edgington