Patents Represented by Attorney, Agent or Law Firm Eric P. Mirabel
  • Patent number: 5100777
    Abstract: An antibody matrix immunoassay device for determination of number and proportion of subpopulations of leukocytes is described. The device can be used to evaluate and monitor the immune status of an individual and to diagnose and monitor the progression of AIDS.
    Type: Grant
    Filed: April 27, 1987
    Date of Patent: March 31, 1992
    Assignee: Tanox Biosystems, Inc.
    Inventor: Tse W. Chang
  • Patent number: 5091313
    Abstract: Antigenic epitopes associated with the extracellular segment of the domain which anchors immunoglobulins to the B cell membrane are disclosed. For IgE, the epitopes are present on IgE-bearing B cells but not basophils or the secreted, soluble form of IgE. The epitope can be exploited for diagnosis.
    Type: Grant
    Filed: November 16, 1988
    Date of Patent: February 25, 1992
    Assignee: Tanox Biosystems, Inc.
    Inventor: Tse-Wen Chang
  • Patent number: 5089603
    Abstract: Antigenic epitopes associated with the extracellular segment of the domain which anchors immunoglobulins to the B cell membrane are disclosed. For IgA, the epitopes are present on IgA-bearing B cells but not the secreted, soluble form of IgA. The epitopes can be exploited for therapy and prophylaxis. For example, antibodies specific for the epitopes associated with the anchor and peptide encompassing the epitope domain of IgA can be used to increase secretory IgA production for the purposes of treating patients with infectious diseases and IgE-mediated allergic diseases.
    Type: Grant
    Filed: December 22, 1989
    Date of Patent: February 18, 1992
    Assignee: Tanox Biosystems, Inc.
    Inventors: Tse-wen Chang, Nancy T. Chang
  • Patent number: 5079344
    Abstract: Antigenic epitopes associated with the extracellular segment of the domain which anchors immunoglobulins to the B cell membrane are disclosed. For IgA, the epitopes are present on IgA-bearing B cells but not the secreted, soluble form of IgA. The epitope can be exploited for therapy and prophylacsis. For example, antibodies specific for the epitopes associated with the anchor and peptide encompassing the epitope domain of IgA can be used to increase secretory IgA production for the purposes of treating patients susceptible with infectious diseases and IgE-mediated allergic diseases.
    Type: Grant
    Filed: June 21, 1989
    Date of Patent: January 7, 1992
    Assignee: Tanox Biosystems, Inc.
    Inventors: Tse-wen Chang, Nancy Chang
  • Patent number: 4894373
    Abstract: Disclosed is a method for treating menopausal symptoms and treating and preventing osteoporosis, wherein a true antiestrogen is administered and estrogen is not. This treatment is effective for female osteoporosis and can also be used to treat male osteoporosis. Examples of true antiestrogens are clomiphene, and its isomers, citrates and derivatives, as well as several other compounds which appear in the specification.
    Type: Grant
    Filed: January 12, 1988
    Date of Patent: January 16, 1990
    Assignee: BCM Technologies, Inc.
    Inventor: Ronald L. Young
  • Patent number: 4782077
    Abstract: A method of treating neurological disorders, in particular Parkinson's disease, is disclosed. The method involves administering an aristolactam, especially Taliscanin, an extract of the root of Aristolochia Taliscana, to an afflicted patient. The dosage is varied in accordance with the patient's response, and generally ranges from 300 to 4000 micrograms per day. Taliscanin has also been shown effective in treating Alzheimer disease and impotence.
    Type: Grant
    Filed: August 20, 1987
    Date of Patent: November 1, 1988
    Assignee: Monoclonetics International, Inc.
    Inventor: Jacinto J. de la Parra
  • Patent number: 4729999
    Abstract: The invention involves a method for treating symptoms secondary to estrogen deficiency without using estrogen. Weakly estrogenic antiestrogens are administered to estrogen deficient women in the absence of estrogen administration. Maximum estrogenic activity is therby obtained and the harmful side effects of estrogen therapy are avoided.
    Type: Grant
    Filed: October 12, 1984
    Date of Patent: March 8, 1988
    Assignee: BCM Technologies
    Inventor: Ronald L. Young
  • Patent number: 4723452
    Abstract: A pumping unit has very large series connected crank and flywheel sheaves. The crank sheave is connected to oscillate a walking beam which reciprocates a horsehead attached to a bridle. The bridle is connected to a polished rod associated with a downhole pump.
    Type: Grant
    Filed: December 16, 1986
    Date of Patent: February 9, 1988
    Assignee: Grooves & Lands, Inc.
    Inventor: Jerry L. Watson
  • Patent number: 4709481
    Abstract: There is disclosed herein an instrument for use in efficiently and sanitarily extricating an ingrown hair from the skin, the instrument comprising an elongate handle and a tip attached to the handle, wherein the tip comprises a curved and tapered blade.
    Type: Grant
    Filed: August 19, 1986
    Date of Patent: December 1, 1987
    Inventor: Milton D. Moore