Patents Represented by Attorney Exelixis, INC

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  • PRMTs as modifiers of the p53 pathway and methods of use
    Patent number: 7049088
    Abstract: Human PRMT genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of PRMT are provided.
    Type: Grant
    Filed: June 5, 2002
    Date of Patent: May 23, 2006
    Assignee: Exelixis, INC
    Inventors: Lori Friedman, Gregory D. Plowman, Marcia Belvin, Helen Francis-Lang, Danxi Li, Roel P. Funke, Rolf Peter Ryseck, Lata Jayaraman, David K. Bol, Matthew Lorenzi