Abstract: Methods and compositions are provided for detecting the presence of nucleic acid sequence variants in a subpopulation of nucleic acid molecules in a biological sample. These methods are particularly useful for identifying individuals with mutations indicative of cancer.
Type:
Grant
Filed:
February 18, 2003
Date of Patent:
August 17, 2010
Assignee:
Genzyme Corporation
Inventors:
Anthony P. Shuber, Lisa Kann, Duncan Whitney