Abstract: 3,4-Disubstituted-4-aryl-piperidine compounds are disclosed. Pharmaceutical compositions containing the 3,4-disubstituted-4-aryl-piperidine compounds and methods of their pharmaceutical uses are also disclosed. The compounds disclosed are useful, inter alia, as antagonists of opioid receptors.
Type:
Grant
Filed:
March 17, 2003
Date of Patent:
June 3, 2008
Assignee:
Adolor Corporation
Inventors:
Roland Ellwood Dolle, Bertrand Le Bourdonnec