Abstract: The invention provides a new class of compounds exhibiting an inhibitory effect on neuraminidase (NA), hemagglutinin (HA) and structural M2 protein bearing viruses. These compounds are also useful as inhibitors of the replication factors of hepatitis virus type C (HVC). The invention also describes pharmaceutical compositions containing the compounds of the invention either alone or in combination admixed with a suitable and pharmaceutically acceptable carrier.

Abstract: A flow measurement cartridge assembly for measuring liquid flow in a partially filled channel and a method for measuring liquid flow using the cartridge assembly, the cartridge assembly comprising: a frame for insertion into a discharge opening of the channel; a level detector secured in the frame for determining a liquid level in the channel; and at least one flow measurement device secured in the frame.

Abstract: A convertible rotary seal has a housing for receiving a polish rod. A mandrel is rotatably mounted in the seal housing and surrounds the polish rod. A wear sleeve surrounding the mandrel engages a primary seal. A secondary seal engages the mandrel and polish rod and rotates therewith but may be converted for use as a static seal if necessary. A locking mechanism selectively secures the mandrel in a stationary orientation with respect to the seal housing. Fluid that leaks past the primary seal will be detectible through an external orifice. If a leak in the primary seal is detected via the external port, then the mandrel may be secured in a stationary orientation with respect to the housing and the secondary seal may be reconfigured to operate as a stationary seal until such time as the rotary sealing unit can be overhauled.

Abstract: There is provided herein a sensor for determining relative displacement between two surfaces which utilizes two optically conductive members that have been mounted in proximity to each other, whereby the amount of displacement between the two surfaces may be determined by measurement of the magnitude of the intensity of light transmitted through them. The instant invention preferably utilizes two planar light transmitting surfaces—an emitter and a receiver—which are free to move laterally with respect to each other and are positioned so that when light is introduced into the emitter some proportion of that light falls on the receiver. By electronically monitoring the intensity of light impinging on the receiver an estimate of the amount of overlap between the two optical surfaces and, thus, an estimate of the relative displacement between them, may be obtained.

Abstract: Cobalt catalysts, and processes employing these inventive catalysts, for hydrocarbon synthesis. The inventive catalyst comprises cobalt on an alumina support and is not promoted with any noble or near noble metals. In one aspect of the invention, the alumina support preferably includes a dopant in an amount effective for increasing the activity of the inventive catalyst. The dopant is preferably a titanium dopant. In another aspect of the invention, the cobalt catalyst is preferably reduced in the presence of hydrogen at a water vapor partial pressure effective to increase the activity of the cobalt catalyst for hydrocarbon synthesis. The water vapor partial pressure is preferably in the range of from 0 to about 0.1 atmospheres.

Abstract: A microprocessor based bed patient monitor receives electronic signals from a mat sensing the presence of a patient. The monitor aural alarm system includes a loudspeaker driven by a power amplifier responsive to an input signal derived from a programmable volume control. The processor synthesizes any one of multiple alarm sounds under software control, operates the programmable volume control of the alarm system and activates and deactivates the alarm in response to the electronic signals received from the sensor and a user interface.

Abstract: The inventive connector includes a tubular dielectric external element within which is disposed an internal conductive element. Two ends of wire or coaxial cable are pushed into the device. The internal conductive element has skiving edges at each end which separate the conductors from the insulating layers. The conductors contact the internal conductive element to form an electrical connection while the skived insulation layers are used to further insulate the device and to apply a holding pressure.