Patents Represented by Attorney Fernando I. Santos, Jr.

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  • Factor VII or VIIa polypeptide variants
    Patent number: 7700733
    Abstract: The present invention relates to novel polypeptide variants of factor VII (FVII) or factor VIIa (FVIIa) polypeptides, where said variants comprise an amino acid substitution in position 10 and 32 and where said variants further comprise a sugar moiety covalently attached to an introduced in vivo N-glycosylation site located outside the Gla domain. Such polypeptide variants are useful in therapy, in particular for the treatment of a variety of coagulation-related disorders, such as trauma.
    Type: Grant
    Filed: April 29, 2003
    Date of Patent: April 20, 2010
    Assignee: Bayer HealthCare LLC
    Inventors: Jesper Mortensen Haaning, Kim Vilbour Andersen