Patents Represented by Attorney, Agent or Law Firm Flehr Hohbach Test Albritton & Herbert LLP
  • Patent number: 6232062
    Abstract: The invention relates to nucleic acids covalently coupled to electrodes via conductive oligomers. More particularly, the invention is directed to the site-selective modification of nucleic acids with electron transfer moieties and electrodes to produce a new class of biomaterials, and to methods of making and using them.
    Type: Grant
    Filed: August 14, 1997
    Date of Patent: May 15, 2001
    Assignee: Clinical Micro Sensors, Inc.
    Inventors: Jon Faiz Kayyem, Stephen D. O'Connor
  • Patent number: 6228359
    Abstract: A method for treating autoimmune disease by removing peripheral blood mononuclear cells from a patient, treating the mononuclear cells with an inhibitory composition that suppresses immunoglobulin production, and reintroducing the treated cells to the patient. The inhibitory composition can be IL-2, TGF-&bgr;, or a CD2 activator.
    Type: Grant
    Filed: November 5, 1998
    Date of Patent: May 8, 2001
    Assignee: University of Southern California
    Inventor: David A. Horwitz
  • Patent number: 6227195
    Abstract: The present invention relates to a method of introducing biologic materials into the conducting airways of the bronchial system. The invention involves the use of a liquid carrier or suspension for the biologic materials, delivered in relatively large droplet form at a velocity greater than the air velocity of the normally breathing subject. This method also can be used for localized delivery of such biologic materials, including diagnostic and imaging agents, into other gas-filled body cavities.
    Type: Grant
    Filed: February 3, 1997
    Date of Patent: May 8, 2001
    Assignee: Genentech, Inc.
    Inventor: Igor Gonda
  • Patent number: 6229632
    Abstract: A differential method of improving the carrier to noise ratio of optically transmitted amplitude modulated signals without affecting the fidelity of the transmitted signals is disclosed. The disclosed method improves over prior art methods by utilizing a single transmission fiber transmitting two wavelengths that are modulated out of phase by a single Mach Zehnder type modulator. The received light is separated into two components at two wavelengths and each wavelength is received by a photodetector. The two photodetector outputs are differentially combined to produce an output with improved signal to noise ratio resulting in improved bit error rates in digital transmissions. The invention is also useful in fiber optic analog transmission systems such as those used to distribute AM-VSB Cable Television programming, wherein the differential method improves the carrier to noise ratio without increasing the nonlinear components in the signal.
    Type: Grant
    Filed: May 12, 1997
    Date of Patent: May 8, 2001
    Assignee: Ditech Corporation
    Inventor: Salim Jabr
  • Patent number: 6223678
    Abstract: Inflatable kayak having a pneumatically inflatable peripheral tube with elongated side sections which come together fore and aft to form a passenger compartment, a flexible cover encasing the tube and forming a shell against which the tube can be inflated to form a relatively rigid structure. A sheet of tarpaulin material extends across the bottom of the passenger compartment and along the lower and outer sides of the tube, and an inflatable floor cushion rests on the tarpaulin material in the passenger compartment. A seat is provided toward the rear of the passenger compartment, and a splash skirt attached to the cover extends across the passenger compartment between the side sections of the tube in front of the seat.
    Type: Grant
    Filed: January 13, 2000
    Date of Patent: May 1, 2001
    Assignee: Stearns Inc.
    Inventors: Clayton Forbes Haller, Charles Prior Hall
  • Patent number: 6223902
    Abstract: Packaging for glasses having stems, the glasses each having a base, a stem mounted on the base and an open bowl mounted on the stem. A case in the form of a parallelepiped is provided having parallel spaced-apart side walls and parallel spaced-apart end walls adjoining the side walls and top and bottom closures to provide an enclosed space for a plurality of juxtaposed glasses disposed in the space within the case. A base platform is provided having a plurality of spaced-apart wells for receiving the bases of the glasses. A top platform is provided having a plurality of spaced-apart wells receiving the bowls of the glasses. Each of the base platform and the top platform have a plurality of pedestals disposed between the wells and are formed integral therewith.
    Type: Grant
    Filed: August 30, 1999
    Date of Patent: May 1, 2001
    Inventor: Gregory W. Gale
  • Patent number: 6224883
    Abstract: An improved diluent for the preparation of cisplatin suspensions from a lyophilized powder is provided. The diluent contains a pharmaceutically acceptable nonionic surfactant, which improves the accuracy and homogeneity of the therapeutic formulation. The suspension may be used directly, or may be used in preparing gel formulations for direct injection into a neoplastic lesion or surrounding tissue.
    Type: Grant
    Filed: January 26, 1998
    Date of Patent: May 1, 2001
    Assignee: Matrix Pharmaceutical, Inc.
    Inventors: Kathleen V. Roskos, Richard E. Jones, Richard Maskiewicz
  • Patent number: 6225129
    Abstract: Method and apparatus for generating an acid or base, e.g. for chromatographic analysis of anions. For generating a base the method includes the steps of providing a cation source in a cation source reservoir, flowing an aqueous liquid stream through a base generation chamber separated from the cation source reservoir by a barrier (e.g. a charged membrane) substantially preventing liquid flow while providing a cation transport bridge, applying an electric potential between an anode cation source reservoir and a cathode in the base generation chamber to electrolytically generate hydroxide ions therein and to cause cations in the cation source reservoir to electromigrate and to be transported across the barrier toward the cathode to combine with the transported cations to form cation hydroxide, and removing the cation hydroxide in an aqueous liquid stream as an effluent from the first base generation chamber. Suitable cation sources include a salt solution, a cation hydroxide solution or cation exchange resin.
    Type: Grant
    Filed: February 2, 1998
    Date of Patent: May 1, 2001
    Assignee: Dionex Corporation
    Inventors: Yan Liu, Hamish Small, Nebojsa Avdalovic
  • Patent number: 6223886
    Abstract: A system for transporting articles. The transport system includes a conveyor system which includes a transport device for carrying articles between workstations and a drive rail and a support rail for supporting the transport device. The drive rail includes a drive system for propelling the transport device between workstations. At least one shoe carried by the transport device rides on the support rail for movably supporting the transport device on the support rail. The transport system also includes a protective container including a housing having an interior compartment for supporting a plurality of articles. The bottom surface of the housing is configured to engage the drive system such that actuation of the drive system propels the housing along the drive and support rails. At least one shoe carried by the housing is configured to ride on the support rail of the conveyor system to movably support the housing on the support rail.
    Type: Grant
    Filed: June 24, 1998
    Date of Patent: May 1, 2001
    Assignee: Asyst Technologies, Inc.
    Inventors: Anthony C. Bonora, Richard H. Gould
  • Patent number: 6220518
    Abstract: An apparatus and process for individual adjustment of the temperature set points of a plurality of VAV devices (27, 29) in an HVAC system. The process includes the step of coupling each of a plurality of computers (34) located in a plurality of offices or spaces (22) for input of a temperature set point signal. The computers (34) are coupled to the VAV devices (27, 29) such that a selected computer will input or adjust the temperature set point of only VAV devices (27, 29) located in the same space (22) as the computer (34). Such coupling can be accomplished through direct electrical connections (33), transmitted signals (37, 38), or the use of computer networks (36, 42) which are connected to the VAV devices (27, 29) directly or through the building HVAC control network (32).
    Type: Grant
    Filed: May 13, 1999
    Date of Patent: April 24, 2001
    Assignee: Acutherm L.P.
    Inventors: James R. Kline, Matthew L. Costick
  • Patent number: 6222227
    Abstract: Memory cell having a floating gate with lateral edges which are aligned directly above edges of the active area in the substrate, a control gate positioned directly above the floating gate, and a select gate spaced laterally from the control gate. The floating gate has a bottom wall and side walls which face corresponding walls of the control gate in capacitive coupling relationship, with the height of the side walls being on the order of 80 to 160 percent of the width of the bottom wall. In some embodiments, the floating gate is wider than the overlying control gate and has projecting portions which overlie the source and drain regions of the stack transistor.
    Type: Grant
    Filed: August 9, 1999
    Date of Patent: April 24, 2001
    Assignee: Actrans System Inc.
    Inventor: Chiou-Feng Chen
  • Patent number: 6220052
    Abstract: Apparatus for liquefying natural gas supplied from a source comprising a compressor for compressing the natural gas. A chiller reduces the temperature of the compressed gas, a heat exchanger for further cooling the cooled compressed gas. A Joule-Thompson valve is provided having an inlet and an orifice in communication with the inlet and the dewar for changing the size of the orifice. A pipe is connected from the heat exchanger to the Joule-Thompson valve and supplies cooled compressed gas to the inlet of the Joule-Thompson valve. The inlet of the Joule-Thompson valve has an inlet pressure. The dewar has a pressure therein substantially less than the pressure in the inlet whereby when the cooled compressed gas from the inlet piping passes through the Joule-Thompson valve there is an expansion of the gas to provide further cooling and liquefaction of a substantial portion of the gas as it passes into the dewar.
    Type: Grant
    Filed: August 17, 1999
    Date of Patent: April 24, 2001
    Assignee: Liberty Fuels, Inc.
    Inventors: Raymond E. Tate, Jr., Harold M. Lee
  • Patent number: 6222762
    Abstract: Maximized multi-state compaction and more tolerance in memory state behavior is achieved through a flexible, self-consistent and self-adapting mode of detection, covering a wide dynamic range. For high density multi-state encoding, this approach borders on full analog treatment, dictating analog techniques including A to D type conversion to reconstruct and process the data. In accordance with the teachings of this invention, the memory array is read with high fidelity, not to provide actual final digital data, but rather to provide raw data accurately reflecting the analog storage state, which information is sent to a memory controller for analysis and detection of the actual final digital data.
    Type: Grant
    Filed: August 7, 1997
    Date of Patent: April 24, 2001
    Assignee: Sandisk Corporation
    Inventors: Daniel C. Guterman, Yupin Kawing Fong
  • Patent number: 6220773
    Abstract: A container for accommodating a fluid, gel-like or pasty medium in a container chamber into which it is possible to dip a brush and which has a removal opening in which there is seated a closure plug which tapers in a stub-like manner into the container chamber and has a through-passage for the introduction of a stem-mounted brush and for stripping the brush when the latter is drawn out of the container chamber, the stem being fastened, by way of an end which is located opposite the brush, on a container head which can be positioned on the removal opening in order for the brush to be stored in the container chamber, it being the case that the container chamber is filled with a breath-freshening oral-hygiene medium into which a brush in the form of an interdental brush for cleaning the spaces between the teeth is inserted in a withdrawable manner.
    Type: Grant
    Filed: January 27, 2000
    Date of Patent: April 24, 2001
    Inventors: Georg Wiegner, Hyeong Sook Kim
  • Patent number: 6221583
    Abstract: The invention relates to nucleic acids covalently coupled to electrodes via conductive oligomers. More particularly, the invention is directed to the site-selective modification of nucleic acids with electron transfer moieties and electrodes to produce a new class of biomaterials, and to methods of making and using them.
    Type: Grant
    Filed: July 24, 1997
    Date of Patent: April 24, 2001
    Assignee: Clinical Micro Sensors, Inc.
    Inventors: Jon Faiz Kayyem, Stephen D. O'Connor, Michael Gozin, Changjun Yu, Thomas J. Meade
  • Patent number: 6222650
    Abstract: Device, method, and system for recording diffractive high resolution text, pictorial, and/or other graphical information is provided which is particularly suited to recording information that would be difficult to reproduce by typical counterfeiting methods. The information recorded may be used to authenticate the recorded item, or indirectly, an item to which the recording is attached. Such items may include legal, financial and commercial instruments, credit cards, and packaging for such items as software, art, and other items where forgery of the item may be a concern. In one embodiment of the invention light is selectively passed by a shutter, and a spatial filter then cleans the beam to remove undesirable frequency components.
    Type: Grant
    Filed: September 1, 1999
    Date of Patent: April 24, 2001
    Assignee: Pacific Holographics Inc.
    Inventor: Michael D. Long
  • Patent number: 6218640
    Abstract: An inductive plasma torch operating at atmospheric pressure is used for wafer or glass substrate processing. Said torch employs a linear type of plasma confinement. This linear torch is particularly suitable for photoresist etching and processes in which it has the advantages of high chemical isotropic etch rate and low plasma damage.
    Type: Grant
    Filed: July 19, 1999
    Date of Patent: April 17, 2001
    Assignee: TimeDomain CVD, Inc.
    Inventor: Simon I. Selitser
  • Patent number: 6214338
    Abstract: A plasma concentrate comprising one of platelets and platelet releasate and from 5 to 400 mg/ml of fibrinogen. The concentrate further includes a physiologically acceptable carrier comprising water and physiologically acceptable inorganic and organic ions at a physiologically acceptable concentration. The fibrinogen in the concentrate is not significantly denatured. A method for processing blood is further provided.
    Type: Grant
    Filed: April 25, 2000
    Date of Patent: April 10, 2001
    Assignee: Plasmaseal LLC
    Inventors: Richard D. Antanavich, Randel Dorian
  • Patent number: 6213955
    Abstract: Apparatus for measuring respiratory air flow from the nostrils of the nose and/or the mouth of a patient comprising a device positioned in the vicinity of the nose and/or mouth of the patient and having at least one acoustic duct receiving respiratory air flow from the patient. A sensor is exposed to the acoustic duct and senses turbulence and/or vibration and/or sound in the air flow in the acoustic duct to provide an electric output signal. The electrical signal is digitally processed to provide a real-time signal indicative of breathing of the patient.
    Type: Grant
    Filed: October 8, 1998
    Date of Patent: April 10, 2001
    Assignee: Sleep Solutions, Inc.
    Inventors: Ahmet Karakasoglu, Karl S. Johnson, George D. Hermann
  • Patent number: D440456
    Type: Grant
    Filed: January 20, 1999
    Date of Patent: April 17, 2001
    Assignee: Sharper Image Corporation
    Inventor: Tristan M. Christianson