Patents Represented by Attorney Folely & Lardner LLP

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  • Materials and methods relating to nucleic acid amplification and profiling
    Patent number: 8105782
    Abstract: The invention provides improved methods for determining the methylation profile of a nucleic acid sequence and for determining one or more base changes in the target nucleic acid sequence as compared to a corresponding control sequence. The methods are one-step methods which can be incorporated with known amplification techniques such as PCR. The invention also provides methods for determining changes in nucleic acid sequences either via their methylation profile or owing to mutations of one or more bases.
    Type: Grant
    Filed: October 23, 2001
    Date of Patent: January 31, 2012
    Assignee: Cancer Research Technology Limited
    Inventor: Per Guldberg