Abstract: The present invention provides a cytotoxic 7 to 25-mer peptide with three or more cationic residues which has one or more non-generic bulky and lipophilic amino acids, as well as esters, amides, salts and cyclic derivatives thereof as well as methods of preparing the peptides, pharmaceutical compositions containing them, and their use as medicaments, particularly as antibacterial or antitumor agents.

Abstract: Reflectors having concave reflecting surfaces (e.g., parabolic reflectors) and electronically controlled beam steering elements are used for rapid, low-diversion, wide-angle and precision steering of optical beams, including laser beams.

Abstract: A cryptographic system (CS) comprised of generators (502), (504), (510), an encryption device (ED), and a decryption device (DD). The generator (502) generates a data sequence (DS) including payload data. The generator (504) generates an encryption sequence (ES) including random numbers. The ED (506) is configured to perform a CGFC arithmetic process. As such, the ED is comprised of a mapping device (MD) and an encryptor. The MD is configured to map the DS and ES from Galois field GF[pk] to Galois extension field GF[pk+1]. The encryptor is configured to generate an encrypted data sequence (EDS) by combining the DS and ES utilizing a Galois field multiplication operation in Galois extension field GF[pk+1]. The generator (510) is configured to generate a decryption sequence (DS). The DD (508) is configured to generate a decrypted data sequence by performing an inverse of the CGFC arithmetic process utilizing the EDS and DS.

Abstract: The present invention relates to a thin film heater (2) including a thin film heat-producing resistor, and a first and a second thin film electrodes (22, 24) electrically connected to the thin film heat-producing resistor to apply voltage to the thin film heat-producing resistor. In the thin film heater (2), at least part of the thin film heat-producing resistor is light transmissive. Preferably, the first thin film electrode (22), the thin film heat-producing resistor and the second thin film electrode (24) are laminated in the film thickness direction in the mentioned order. The present invention further provides an analytical instrument (X) provided with the thin film heater (2).

Abstract: A hub (14) for a triple lumen catheter (12) especially for use with a catheter assembly (10) such as for hemodialysis. The hub (14) has a body (40) with one distal opening (58) for insertion thereinto of a proximal end portion (26) of the catheter (12), and three proximal openings (52,54,56) for insertion thereinto of distal end portions (74,76,78) of three extension tubes (16,18,20) each associated with one of the catheter's three lumens (30,32,34). The hub provides three passageways (68,70,72) extending from respective proximal openings to respective interior openings (60,62,64) in communication with the one distal opening (58), for establishing fluid communication between each extension tube (16,18,20) and its associated catheter lumen (30,32,34). Preferably, the hub is insert molded to respective end portions of the catheter (12) and the extension tubes (16,18,20).

Abstract: The present invention enhances a golf tournament using novel tournament scoring and novel rules that include allowing viewer interaction with a live tournament to affect the outcome of the tournament. In a match play golf tournament, the number of tournament points awarded to a match winning team is directly proportional to a sum of the difference in the number of holes won and the number of holes left to play. In addition, elected spectators of the event may participate in a team's compliance with one or more of the tournament rules, such as selecting a player whose results will be counted double. The tournament is preferably based on the Ryder cup format, but condensed into a single day.

Abstract: Disclosed herein are non-competitive NMDA receptor antagonists having chemical structures similar to that of phencyclidine (PCP). These antagonists contain a polycyclic ring structure in place of the cycloalkyl ring of PCP. The antagonists also differ from PCP in that they include an electron withdrawing group, a hydroxyl group, or an amine group at the para position of the phenyl ring. The antagonists disclosed herein are useful for treating or ameliorating a symptom of ailments associated with over excitation of cells (e.g., neurons) that express NMDA receptors. Examples of ailments that can be treated and for which symptoms can be ameliorated include epilepsy, neurodegenerative disease (e.g., Alzheimer's and Parkinson's diseases), drug addiction, neuropathic pain, and neuronal and glutamate-dependent tumors.

Abstract: A secure file service includes a cryptographic processor (302, 602) and a secure file system (301, 601). The cryptographic processor is comprised of a trusted microprocessor and a trusted operating system executing on the trusted cryptographic processor. The cryptographic processor includes hardware and software for accessing at least one classified data file from the secure file system, decrypting the classified data file, and serving the classified data file in decrypted form to a secure user processor (402, 502, 702) that has requested the file. The secure file system can be either a single-level secure file system (301) or a multi-level secure file system (601).

Abstract: A three-phase bridge rectifier circuit (TPBRC) connectable to an AC voltage source (102, 104, 106) via input lines (151, 153, 155) and to a load (199) via output lines (159, 157). The AC voltage source supplies the TPBRC (100) with AC voltage waveforms (302, 304, 306) that differ in phase by a certain amount. The TPBRC includes three series transistor combinations (110/112, 114/116, 118/120) connected across the output lines. A plurality of diodes (190, 128, 198, 148, 113, 168) are connected between a drain (152, 122, 162, 132, 172, 142) of one of the field effect transistors (110, 112, 114, 116, 118, 120) and a gate (154, 124, 164, 134, 174, 144) of a different one of the field effect transistors. A voltage divider (192/188, 130/140, 107/196, 150/160, 115/111, 170/180) and a voltage clamping device (194, 138, 109, 158, 119, 178) is provided for each field effect transistor.

Abstract: The present invention relates to compositions and methods for producing a complex drug delivery system which specifically targets cancer cells, has an increase in cellular uptake, is cytotoxic, and suppresses antiapoptotic cellular defenses.

Abstract: The present invention provides devices, small interfering RNA, and methods for treating a neurodegenerative disorder comprising the steps of surgically implanting a catheter so that a discharge portion of the catheter lies adjacent to a predetermined infusion site in a brain, and discharging through the discharge portion of the catheter a predetermined dosage of at least one substance capable of inhibiting production of at least one neurodegenerative protein. The present invention also provides valuable small interfering RNA vectors, and methods for treating neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, Huntington's disease, Spinocerebellar Ataxia Type 1, Type 2, Type 3, and/or dentatorubral-pallidoluysian atrophy.

Abstract: A flight recorder includes an information input device, heat sensitive memory device electrically connected to the information input device, and housing enclosing the heat sensitive memory device. The housing is made with a first material and having a plurality of openings made through the housing. A sacrificial material is disposed between the housing and heat sensitive memory device. The sacrificial material having a lower melting temperature than the first material such that the sacrificial material changes state and egresses through the openings in the housing when exposed to heat to create an air gap between the housing and heat sensitive memory device. The first material includes nickel and the sacrificial material includes aluminum. A heat insulating layer is disposed between the sacrificial material and heat sensitive memory device. A second sacrificial material is disposed between the heat insulating layer and heat sensitive memory device.

Abstract: The present invention provides a composition comprising a cefditoren, or a salt, derivative, prodrug, or other form thereof, for example, cefditoren pivoxil, useful in the treatment and prevention of infections and related conditions. The invention provides a composition which comprises nanoparticulate particles comprising the cefditoren, or a salt, derivative, prodrug, or other form thereof and at least one surface stabilizer. The nanoparticulate particles have an effective average particle size of less than about 2000 nm. The invention provides also a composition that delivers a cefditoren, or a salt, derivative, prodrug, or other form thereof, or nanoparticles comprising the same, in a pulsatile or continuous manner.

Abstract: A component from a substrate processing chamber which has plasma process residues on both its internal and external surfaces, is removed from the processing chamber, and transferred to a cleaning chamber. The component is exposed to an energized cleaning gas in the cleaning chamber, and the cleaning gas is exhausted from below the component so that the cleaning gas cleans off the residues on both the internal and external surfaces of the component. It has been determined that the cleaning gas can also repair surface defects in the component.

Abstract: The present invention relates to a biochip readout device for analyzing and reading out biochips in a rotation manner such that a biochip having been adopted in a non-rotation manner is mounted on an optical disc, and a diagnostic system with a biochip readout device.

Abstract: The present invention provides materials and methods for modulating FATP expression and/or activity in vivo. The materials and methods have numerous diagnostic, prophylactic, and therapeutic applications for various diseases and conditions that are influenced by FATPs, or characterized by excessive or inadequate FATP expression or activity.

Abstract: The instant invention provides methods, systems and reagents for immunodetection involving novel epitope tags and antibodies which recognize these new epitope tags as well as the antibodies which detect the FLAG epitope tag. Fusion proteins comprising the epitope tags, as well as methods of purifying these proteins and kits detecting these proteins are also provided.

Abstract: Positive logic circuits, systems and methods using MOSFETs operated in a depletion-mode, including electrostatic discharge protection circuits (ESD), non-inverting latches and buffers, and one-to-three transistor static random access memory cells. These novel circuits supplement enhancement-mode MOSFET technology and are also intended to improve the reliability of the complementary metal-oxide-semiconductor (CMOS) integrated circuit (IC) products.