Abstract: Method and system for creating a fused image from an image pair comprising a high resolution panchromatic image and lower resolution multi-spectral image. The method includes obtaining image data (204) defining a first image of a panchromatic image type and a second image of a multi-spectral image type. The first image has a first spatial resolution and a first spectral resolution. The second image has a second spatial resolution which is lower than the first spatial resolution and a second spectral resolution higher than the first spectral resolution. The method also includes a step (212) of concurrently calculating a point-spread function for down-sampling the first image to the second spatial resolution, and a set of weights for down-sampling the second image to the first spectral resolution.

Abstract: A novel isoform of tropomyosin is disclosed. The isoform is closely related to epithelial human tropomyosin (hTM) and more particularly to hTM5 except the last coding exon. The novel isoform, is called TC22. Northern blot analysis with TC22-specific probe revealed that normal culture cell lines and normal epithelial tissues expressed very little, if at all, TC22 message, whereas their transformed counterparts and tumor tissues including dysfunction of the alimentary canal, significantly increased the expression of TC22. Assays directed at determining the level of TC22 are useful in diagnostics and therapeutics of dysfunction of the alimentary canal. Specific antibodies and mimics for TC22 are also disclosed for use in diagnostics and therapeutics of dysfunction of the alimentary canal.