Patents Represented by Attorney France Cote Bereskin and Parr

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  • Oligonucleotide inhibitors of MBD2/DNA demethylase and uses thereof
    Patent number: 7465714
    Abstract: Oligonucleotide inhibitors that inhibit expression of a mammalian MBD2/DNA demethylase (MBD2/dMTase) are provided. The oligonucleotide inhibitors can be used to inhibit the growth or proliferation of tumor cells in vitro and in vivo. The use of the oligonucleotide inhibitors in the treatment of cancer and methods of identifying potential target genes for cancer therapy or diagnosis using the oligonucleotide inhibitors are also provided.
    Type: Grant
    Filed: June 20, 2003
    Date of Patent: December 16, 2008
    Assignee: McGill University
    Inventors: Moshe Szyf, Paul Campbell