Patents Represented by Attorney Francis F. Bigley
  • Patent number: 5837228
    Abstract: A bioerodible controlled release dosage form is disclosed comprising a polymer formed by condensing beneficial agents having a hydroxyl functionality of two or more with diketene acetals or divinyl ethers which delivers beneficial agents to a biological environment of use. A statistically significant portion of the beneficial agent is covalently bonded within the polymer matrix.
    Type: Grant
    Filed: September 2, 1992
    Date of Patent: November 17, 1998
    Assignee: Merck & Co., Inc.
    Inventors: Chung Shih, Gaylen M. Zentner, Randall V. Sparer, R. Lee Seward